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Sleeve Gastrectomy in Mice using Surgical Clips

Article DOI: 10.3791/60719-v • 05:16 min • November 14th, 2020
November 14th, 2020 •
1,2,3, 4, 5, 3,6,7,8,9, 3,6,7
1Cardiovascular Division, Internal Medicine Department, Min-Sheng General Hospital, 2Department of Nutrition and Health Sciences, School of Healthcare Management, Kai-Nan University, 3Institute of Clinical Medicine, National Yang-Ming University, 4Food Science and Biotechnology, College of Biotechnology and Bioresources, University of Da-Yeh, 5Department of Surgery, Min-Sheng General Hospital, 6Department of Critical Care Medicine, Taipei Veterans General Hospital, 7Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, 8Division of Cardiology, Heart Center, Cheng-Hsin General Hospital, 9Taipei Medical University

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Summary
Automatic Translation

The prevalence of diabetes and obesity is continuously increasing worldwide. The mechanisms between diabetes, obesity and their associated mortality and co-morbidities need to be further investigated. Here, we present a protocol for sleeve gastrectomy (SG) in animals as an uncomplicated preclinical model of bariatric surgery.

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Sleeve Gastrectomy Mice Surgical Clips Metabolic Effects Insulin Resistance Assessable Mouse Model Bariatric Surgery Obesity Type 2 Diabetes Treatment Anesthesia Carbomer 0.2%eye Gel Surgical Table Depilatory Cream Povidone-iodine Solution Alcohol Magnifying Dissecting Microscope Magnifier Bleeding Hypovolemic Shock Midline Incision Curved Smooth Serrated Micro-forceps Stomach Externalization Intestine Warm Saline Moistened Gauze Gastrosplenic Ligament
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