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JoVE Journal Developmental Biology
Brug af Trowell-type organkultur til at studere regulering af dental stamceller
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Brug af Trowell-type organkultur til at studere regulering af dental stamceller

Article DOI: 10.3791/62462-v • 06:22 min • July 8th, 2021
July 8th, 2021 •
*1,2, *1
1Research Program in Developmental Biology, Institute of Biotechnology, University of Helsinki, 2Department of Oral and Maxillofacial diseases, Faculty of Medicine, University of Helsinki
* These authors contributed equally

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Trowell-typen organkulturmetode er blevet brugt til at optrævle komplekse signalnetværk, der styrer tandudvikling og for nylig til at studere regulering involveret i stamceller i den kontinuerligt voksende musefortænder. Fluorescerende dyremodeller og levende billeddannelsesmetoder letter dybdegående analyser af tandstamceller og deres specifikke nichemikromiljø.

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Udviklingsbiologi udgave 173 organkultur tand musefortænder cervikalsløjfe epitelstamceller stamcelleniche fluorescerende reportermodeller
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