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Journal / Biochemistry / Bioluminescerende optogenetik 2.0: Udnyttelse af…
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Biochemistry

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JoVE Journal Biochemistry
Bioluminescerende optogenetik 2.0
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Bioluminescerende optogenetik 2.0: Udnyttelse af bioluminescens til at aktivere fotosensoriske proteiner in vitro og in vivo

Article DOI: 10.3791/62850-v • 07:19 min • August 4th, 2021
August 4th, 2021 •
1,2, 1, 1, 1,2,3
1College of Medicine, Central Michigan University, 2Biochemistry, Cell and Molecular Biology Program, Central Michigan University, 3Neuroscience Program, Central Michigan University

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Bioluminescens-lys udsendt af et luciferaseenzym, der oxiderer et lille molekylesubstrat, et luciferin-kan udnyttes til at aktivere fotosensoriske proteiner og derved tilføje en anden dimension til lysstimulering og muliggøre manipulation af en lang række lysmedierede funktioner i celler på tværs af tidsmæssige og rumlige skalaer.

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