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JoVE Journal Genetics
Het bepalen van de rol van maternale tot expressie gebrachte genen in de vroege ontwikkeling met maternale crispants
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Het bepalen van de rol van maternale tot expressie gebrachte genen in de vroege ontwikkeling met maternale crispants

Article DOI: 10.3791/63177-v • 10:08 min • December 21st, 2021
December 21st, 2021 •
1, 1, 1
1Laboratory of Genetics, University of Wisconsin-Madison

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Vroege ontwikkeling is afhankelijk van moederlijk overgeërfde producten en de rol van veel van deze producten is momenteel onbekend. Hierin beschreven we een protocol dat CRISPR-Cas9 gebruikt om fenotypen met maternale effecten in een enkele generatie te identificeren.

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Genetica vroege ontwikkeling CRISPR-Cas9 maternal-effect zebravis genome editing reverse genetics
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