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Journal / Genetics / Bestemmelse af moderens udtrykte geners rolle i…
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JoVE Journal Genetics
Bestemmelse af moderens udtrykte geners rolle i tidlig udvikling med moderens sprøde stoffer
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Bestemmelse af moderens udtrykte geners rolle i tidlig udvikling med moderens sprøde stoffer

Article DOI: 10.3791/63177-v • 10:08 min • December 21st, 2021
December 21st, 2021 •
1, 1, 1
1Laboratory of Genetics, University of Wisconsin-Madison

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Tidlig udvikling er afhængig af moderens arvede produkter, og mange af disse produkters rolle er i øjeblikket ukendt. Heri beskrev vi en protokol, der bruger CRISPR-Cas9 til at identificere fænotyper med modereffekt i en enkelt generation.

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Genetik udgave 178 tidlig udvikling CRISPR-Cas9 modereffekt zebrafisk genomredigering omvendt genetik
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