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Ediciones precisas mediadas por CRISPR-Cas9 en corazones de pez cebra
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Ediciones precisas mediadas por CRISPR-Cas9 en corazones de pez cebra

Article DOI: 10.3791/64209-v • 06:52 min • September 13th, 2022
September 13th, 2022 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1Department of Biomedical Physiology and Kinesiology, Simon Fraser University

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Este protocolo describe un enfoque para facilitar ediciones precisas en embriones de pez cebra utilizando la tecnología CRISPR-Cas9. Se presenta una tubería de fenotipado para demostrar la aplicabilidad de estas técnicas para modelar una variante genética asociada al síndrome de QT largo.

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Biología Número 187 CRISPR-Cas9 pez cebra reparación dirigida por homología hERG Síndrome de QT largo
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