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JoVE Journal Biology
En modificeret teknik til tværgående aortaindsnævring hos mus
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En modificeret teknik til tværgående aortaindsnævring hos mus

Article DOI: 10.3791/64386-v • 04:52 min • August 18th, 2022
August 18th, 2022 •
*1,2, *1,2, *1,2, 1,2
1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 2Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
* These authors contributed equally

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Denne protokol beskriver en modificeret og forenklet teknik med en minimalt invasiv tværgående aortaindsnævring (TAC) procedure ved hjælp af en selvfremstillet retraktor. Denne procedure kan udføres uden ventilator eller mikroskop og introducerer trykoverbelastning, hvilket i sidste ende fører til hjertehypertrofi eller hjertesvigt.

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Biologi nr. 186
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