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JoVE Journal Biology
En modifierad teknik för tvärgående aortaförträngning hos möss
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En modifierad teknik för tvärgående aortaförträngning hos möss

Article DOI: 10.3791/64386-v • 04:52 min • August 18th, 2022
August 18th, 2022 •
*1,2, *1,2, *1,2, 1,2
1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 2Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
* These authors contributed equally

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Detta protokoll beskriver en modifierad och förenklad teknik med en minimalt invasiv transversell aorta constriction (TAC) procedur med hjälp av en självtillverkad retractor. Denna procedur kan utföras utan ventilator eller mikroskop och introducerar trycköverbelastning, vilket så småningom leder till hjärthypertrofi eller hjärtsvikt.

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Biologi nummer 186
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