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Una técnica modificada para la constricción aórtica transversa en ratones
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Una técnica modificada para la constricción aórtica transversa en ratones

Article DOI: 10.3791/64386-v • 04:52 min • August 18th, 2022
August 18th, 2022 •
*1,2, *1,2, *1,2, 1,2
1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 2Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
* These authors contributed equally

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El presente protocolo describe una técnica modificada y simplificada con un procedimiento de constricción aórtica transversa (TAC) mínimamente invasivo utilizando un retractor de fabricación propia. Este procedimiento se puede realizar sin un ventilador o microscopio e introduce sobrecarga de presión, lo que eventualmente conduce a hipertrofia cardíaca o insuficiencia cardíaca.

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Biología Número 186
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