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Journal / Neuroscience / Sıçanlarda Tibial Nöroma Transpozisyon Modelinde…
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JoVE Journal Neuroscience
Sıçanlarda Tibial Nöroma Transpozisyon Modelinde Cerrahi ve Davranışsal Test
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Sıçanlarda Tibial Nöroma Transpozisyon Modelinde Cerrahi ve Davranışsal Test

Article DOI: 10.3791/64659-v • 07:23 min • January 6th, 2023
January 6th, 2023 •
1, 2, 3, 1
1Department of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Utrecht University, 2Axogen, 3Center for Translational Immunology, University Medical Center Utrecht, Utrecht University

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Bu protokol, tibial sinirin lezyonunu ve ardından proksimal sinir ucunun subkutan pretibial veya lateral pozisyona doğru transpozisyonunu gerektiren tibial nöroma transpozisyon modelini tanımlar. Nöroma ağrısı ve plantar hiperaljezinin davranışsal testleri, Von Frey monofilamentleri kullanılarak ölçülür.

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