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JoVE Journal Engineering
Perfusion hépatique Ex vivo Ex Vivo Normothermic chez la souris
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Perfusion hépatique Ex vivo Ex Vivo Normothermic chez la souris

Article DOI: 10.3791/65363-v • 13:14 min • September 25th, 2023
September 25th, 2023 •
1, 2, 1,3, 1, 1
1Experimental Transplantation Surgery, Department of General, Visceral and Vascular Surgery, Jena University Hospital, 2Institute of Pathology, Klinikum Chemnitz GmbH, 3Department of Pathology, Faculty of Veterinary Medicine, Menoufia University

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Un système de perfusion hépatique ex vivo normothermique (NEVLP) a été créé pour les foies de souris. Ce système nécessite de l’expérience en microchirurgie mais permet des résultats de perfusion reproductibles. La capacité d’utiliser des foies de souris facilite l’étude des voies moléculaires pour identifier de nouveaux additifs perfusats et permet l’exécution d’expériences axées sur la réparation d’organes.

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