Lumbar Spine Injection

Lumbar spine injection is a minimally invasive procedure that delivers medication into or near structures of the lower spine to diagnose or manage pain and related functional limitations. Depending on the target, clinicians use anatomical landmarks or imaging guidance to place a needle near a nerve root, facet joint, or epidural space, where local anesthetics can interrupt pain signaling and corticosteroids may reduce inflammation. In behavioral research and clinical care, changes in pain intensity, movement, sleep, and activity can help assess how spinal pain influences behavior and daily function. The procedure also supports targeted treatment planning when conservative approaches provide insufficient relief.

Lumbar Spine Injection - Related Videos

Research

JoVE EoE - Large Animal Models

Intrathecal Placement of Lumbar Drain: A Technique to Withdraw Cerebrospinal Fluid from the Lumbar Spine in Porcine Model

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2025

This video describes the technique of intrathecal placement of a lumbar drain in a porcine ischemic model, which helps in draining the cerebrospinal fluid to a drainage system. The cerebrospinal fluid pressure is monitored by the drainage system, and fluid is drained to maintain a constant cerebrospinal fluid pressure.

A Mouse Model of Lumbar Spine Instability

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Cited by 14 •

2021

We developed a lumbar intervertebral disc degeneration mouse model by resection of L3–L5 spinous processes along with supra- and inter-spinous ligaments and detachment of paraspinous muscles.

Surgical Induction of Lumbar Spine Instability in Mouse Model: A Surgical Procedure for the Resection of the Lumbar Spinous Processes and Connected Ligaments in Murine Model

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2025

In this video, we describe the surgical procedure to induce lumbar spine instability in a mouse model by resecting the Lumbar L3 to L5 spinous process along with supraspinous and interspinous ligaments.

An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model

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2017

Here, we introduce a method to evaluate transpedicular screws by using an in vivo porcine lumbar spine model.

Harvesting DRG from Rat Spine: A Procedure to Extract Dorsal Root Ganglion from the Spine of a Rat Model

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2023

In this video, we demonstrate the extraction of dorsal root ganglion or DRG from a harvested rat spine for downstream applications.

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