Acclimatization

Acclimatization is the reversible adjustment of an organism’s physiology, behavior, or biochemistry to changing environmental conditions, allowing it to maintain function and survival. These changes develop over days to weeks as environmental cues alter processes such as ventilation, circulation, metabolism, water balance, or enzyme activity; for example, exposure to high altitude can increase breathing and red blood cell production to improve oxygen delivery. Studying acclimatization helps biologists explain how organisms respond to temperature, oxygen availability, salinity, and other stresses, while informing research in ecology, evolution, conservation, and human health.

Acclimatization - Related Videos

Education

JoVE Science Education - Basic Biology

Transport and Acclimatization of Rodents for Research

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Transporting rodents for research requires procedures that minimize stress and maintain animal welfare during movement to minimize the influence on experimental outcomes. Transport cages should provide adequate ventilation,...

Research

JoVE EoE - Danio rerio (zebrafish)

Zebrafish Avoidance and Thigmotaxis Assay: A High-Throughput Method to Examine Larval Behavior in Response to Aversive Visual Stimulus

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2023

The video describes the avoidance and thigmotaxis assay of zebrafish larvae. The video examines the behavior of zebrafish larvae in response to visual aversive stimulus.

Recordings of Neural Circuit Activation in Freely Behaving Animals

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Cited by 7 •

2009

Non-invasive measurements of neural activity patterns in freely behaving animals are obtained by combining neurophysiological recordings with high speed videography.

Measuring Respiratory Function in Mice Using Unrestrained Whole-body Plethysmography

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Cited by 70 •

2014

The assessment of respiratory physiology has traditionally relied upon techniques, which require restraint or sedation of the animal. Unrestrained whole-body plethysmography, however, provides precise, non-invasive, quantitative analysis of respiratory physiology in animal models. In addition, the technique allows repeated respiratory assessment of mice allowing for longitudinal studies.

Fear Conditioning

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2023

Fear Conditioning is a type of learning in which an association is established between a negative unpleasant event and a harmless stimulus. This leads to a fear of the harmless stimulus. This process is largely mediated by the amygdala, which is a brain region involved in emotions and stress reactions. Fear conditioning can be utilized in several ways to understand different aspects of learning and memory. This video presents an overview of the principles behind fear conditioning, discusses the...

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