Airborne Particle Exposure

Airborne particle exposure is contact with solid or liquid particles suspended in air, including dust, droplets, and fine particulate matter, and matters because inhaled particles can interact with biological tissues. Particle size, shape, composition, and concentration influence how particles move through the respiratory tract, where larger particles may deposit in the nose and airways while smaller particles can reach deeper lung regions and trigger cellular or inflammatory responses. In biology, studying airborne particle exposure supports research on respiratory health, immune defense, environmental disease, workplace safety, and pollutant toxicity. Exposure measurements and controlled laboratory models help relate particle characteristics to biological outcomes and guide risk assessment.

Airborne Particle Exposure - Related Videos

Research

JoVE Journal - Biology
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An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing

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Cited by 45 •

2020

Described is the cell culture and exposure method of an in vitro bronchial model for realistic, repeated inhalation exposure to particles for toxicity testing.

Research

JoVE Journal - Medicine

Construction and Evaluation of a Murine Calvarial Osteolysis Model by Exposure to CoCrMo Particles in Aseptic Loosening

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Cited by 9 •

2018

This manuscript describes a murine calvarial osteolysis model by exposure to CoCrMo particles, which constitutes an ideal animal model for assessing the interactions between wear particles and various cells in aseptic loosening.

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens

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Cited by 11 •

2016

In the current climate of scarce resources, new technologies are emerging that allow researchers to conduct studies cheaper, faster and with more precision. Here we describe the development of a bead-based salivary antibody multiplex immunoassay to measure human exposure to multiple environmental pathogens simultaneously.

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface

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Cited by 2 •

2020

We present a robust, transferable and predictive in vitro exposure system for the screening and monitoring of airborne particles concerning their acute pulmonary cytotoxicity by exposing cultivated human lung cells at the air-liquid interface (ALI).

Whole-Body Nanoparticle Aerosol Inhalation Exposures

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Cited by 51 •

2013

A whole-body nanoparticle aerosol inhalation exposure facility was constructed for nano-sized titanium dioxide (TiO2) inhalation toxicology studies. This system provides nano-TiO2 aerosol test atmospheres that have: 1) a steady mass concentration; 2) a homogenous composition free of contaminants; and 3) a stable particle size distribution during aerosol generation.

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