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Whole-Body Nanoparticle Aerosol Inhalation Exposures
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Whole-Body Nanoparticle Aerosol Inhalation Exposures

Whole-Body Nanoparticle Aerosol Inhalation Exposures

DOI:
10.3791/50263-v

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10:11 min

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May 07, 2013

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, , , , , , , , ,
1Department of Physiology and Pharmacology, School of Medicine,West Virginia University , 2Center for Cardiovascular and Respiratory Sciences,West Virginia University , 3National Institute for Occupational Safety and Health

Chapters

  • 00:05Title
  • 01:53Preparatory Steps
  • 02:32Setting Up the Aerosol Generators
  • 03:18Setting Up the Monitoring Equipment
  • 04:33Loading Experimental Animals into the Inhalation Exposure Chamber
  • 05:01Exposing Small Animals to Nanoparticle Aerosols
  • 07:47Results: Maintaining a Test Environment for Whole-body Inhalation Studies
  • 09:35Conclusion

Summary

Automatic Translation

Automatic Translation

A whole-body nanoparticle aerosol inhalation exposure facility was constructed for nano-sized titanium dioxide (TiO2) inhalation toxicology studies. This system provides nano-TiO2 aerosol test atmospheres that have: 1) a steady mass concentration; 2) a homogenous composition free of contaminants; and 3) a stable particle size distribution during aerosol generation.

Tags

Keywords: Nanoparticle AerosolInhalation ExposureWhole-body ExposureAerosol GenerationNano-TiO2Exposure ChamberParticle Size DistributionMass ConcentrationGravimetric AnalysisScanning Mobility Particle SizerElectric Low Pressure ImpactorScanning Electron MicroscopyEnergy Dispersive X-ray Analysis

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