Ear Notching
Ear Notching - Related Videos
09:10
Ear Exam
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2023
Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA This video describes the examination of the ear, beginning with a review of its surface and interior anatomy (Figure 1). The cartilaginous auricle consists of the helix, antihelix, earlobe, and tragus. The mastoid process is positioned just behind the earlobe. The slightly curving auditory canal ends at the tympanic membrane, which transmits sound...
08:01
Stimulation of Notch Signaling in Mouse Osteoclast Precursors
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Cited by 13 •
2017
Notch signaling is a form of cellular communication that relies upon direct contact between cells. To properly induce Notch signaling in vitro, Notch ligands must be presented to cells in an immobilized state. This protocol describes methods for in vitro stimulation of Notch signaling in mouse osteoclast precursors.
03:14
Notch Signaling Pathway
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2021
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule. The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
03:14
Notch Signaling Pathway
0 Views •
2023
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule. The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
01:16
Anatomy of the Ear
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2024
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
FAQs
The code translates a planned combination of ear marks into an identification pattern that can be compared across animals in the same group. Its value depends on applying the pattern consistently and documenting it accurately. When the recorded code matches the animal, researchers can connect that individual with lineage information, treatments, health observations, and experimental outcomes.
Reliable identification depends on three linked factors: a clearly defined code, consistent use of the specialized notcher, and accurate recordkeeping. If the marking technique varies or the resulting pattern is recorded incorrectly, later observations may be assigned to the wrong animal. Appropriate welfare practices also support responsible handling during the identification process.
In some research settings, the tissue removed during marking can also support genotyping, which examines genetic information to distinguish or characterize animals. This creates an additional use for the collected sample beyond visual identification. When combined with the recorded ear pattern, genotype information can strengthen the connection between an animal’s identity and its biological or experimental records.
A typical workflow begins by assigning a predefined identification code, using a specialized notcher to create the corresponding pattern, and recording that pattern with the animal’s other information. In settings where tissue is collected for genotyping, the sample is retained for that purpose. Careful technique and welfare-conscious handling should accompany each stage.
The method is used when groups of livestock or laboratory animals must be tracked as individuals over time. In livestock management, records can remain linked to a particular animal, while laboratory colonies may use the system to organize animals within research groups. The same identification record can support lineage tracking, treatment documentation, health observations, and outcome analysis.
Welfare practices are important because identification must be carried out responsibly rather than treated as a recordkeeping task alone. Appropriate handling should accompany the use of the notcher and the collection of any tissue sample. This supports responsible animal care while helping preserve dependable identification records for later biological observations and research interpretation.