Hydrostatic Pressure Treatment

Hydrostatic pressure treatment is a technique that subjects biological materials to intense, uniform pressure, making it possible to alter or preserve them with limited heating. Pressure is transmitted through a surrounding liquid and compresses samples evenly, disrupting membrane structure, changing protein conformation, and influencing enzyme activity while often maintaining small-molecule bonds. In biology, researchers use this approach to study pressure effects on cells, microorganisms, proteins, and other biomolecules. It also supports nonthermal preservation and processing, helping investigate microbial inactivation, cellular adaptation, protein stability, and the physical conditions that shape biological function.

Hydrostatic Pressure Treatment - Related Videos

Education

JoVE Core - Calculus

Applications of Integration to Find Hydrostatic Pressure

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2026

Hydrostatic force is a fluid's total force at rest on a surface. For a horizontal surface submerged at a fixed depth, the pressure is constant and calculated as the product of fluid density, gravitational acceleration, and depth. In the case of a vertical dam wall submerged in water, this force is not evenly distributed due to the increasing pressure with depth. This variation arises from the cumulative weight of the water above each point. Integration is used to account for the continuous...

Hydrostatic Pressure Force on a Plane Surface

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2025

When a plane surface is submerged in a fluid, hydrostatic forces develop on the surface due to the fluid's pressure. For horizontal surfaces, the pressure exerted by the fluid is uniform because the depth remains constant. The resultant force is determined by the pressure at the given depth multiplied by the area of the surface, and it acts through the centroid of the surface. For vertical surfaces, the pressure varies with depth, increasing as the distance from the fluid's free surface...

Hydrostatic Pressure Force on a Curved Surface

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2025

Hydrostatic pressure on curved surfaces is a fundamental concept in fluid mechanics with broad applications in the civil engineering field. When fluid is in contact with a curved surface, as in a reservoir, dam, or storage tank, it exerts pressure that varies in magnitude and direction along the curved surface. To assess the total hydrostatic force exerted by the fluid on a curved structure, engineers typically isolate the fluid volume adjacent to the surface and analyze the forces acting on...

Research

JoVE EoE - Neurotherapeutics

Assessing Atmospheric Pressure Plasma Treatment in Glucose-Deprived Neuroblastoma Cells

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2025

Source: Yan, X., et. al., New Application of an Atmospheric Pressure Plasma Jet as a Neuro-protective Agent Against Glucose Deprivation-induced Injury of SH-SY5Y Cells. J. Vis. Exp. (2017)The video demonstrates the neuroprotective activity of low-dose atmospheric pressure plasma treatment in glucose-deprived neuroblastoma cells by modulating oxidative stress and enhancing cell viability.

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

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Cited by 5 •

2013

The laser heated diamond anvil cell combined with synchrotron micro-diffraction techniques allows researchers to explore the nature and properties of new phases of matter at extreme pressure and temperature (PT) conditions. Heterogeneous samples can be characterized in situ under high pressure by 2D mapping and combined powder, single-crystal and multigrain diffraction approaches.

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