Lumbar Nerves

Lumbar nerves are paired spinal nerves associated with the lower back that carry sensory information toward the central nervous system and motor commands to muscles and glands, making them essential for movement and sensation in the trunk and lower limbs. Each mixed nerve forms from dorsal sensory and ventral motor roots, exits the vertebral canal through an intervertebral foramen, and joins neighboring nerves in the lumbar plexus; branching pathways then distribute signals according to target tissues. In biology and medicine, their organization helps explain lower-limb innervation, reflexes, and conditions such as nerve-root compression, while guiding neurological examination, imaging, and regional anesthesia.

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JoVE EoE - Neurotherapeutics

Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation

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2025

Source: Wang, L., et.al. Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation. J. Vis. Exp.(2023)This video demonstrates a minimally invasive endoscopic procedure to treat lumbar disc herniation by removing the protruded nucleus pulposus and ruptured annulus fibrosus. The technique decompresses the affected nerve root, alleviates pain, and restores nerve function through targeted tissue resection and radiofrequency modulation.

Circumferential Transforaminal Endoscopic Lumbar Foraminotomy for 360° Exiting Nerve Root Decompression in Patients with Lumbar Foraminal Stenosis

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2026

This protocol describes circumferential transforaminal endoscopic lumbar foraminotomy for 360° decompression of the exiting nerve root in patients with lumbar foraminal stenosis using a step-by-step, landmark-based approach to achieve adequate bony and soft-tissue decompression.

Intrathecal Placement of Lumbar Drain: A Technique to Withdraw Cerebrospinal Fluid from the Lumbar Spine in Porcine Model

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2025

This video describes the technique of intrathecal placement of a lumbar drain in a porcine ischemic model, which helps in draining the cerebrospinal fluid to a drainage system. The cerebrospinal fluid pressure is monitored by the drainage system, and fluid is drained to maintain a constant cerebrospinal fluid pressure.

Laminotomy for Targeted Injection into the Lumbar Dorsal Root Ganglion in a Pig Model

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2025

Source: Unger, M. D., et al., Laminotomy for Lumbar Dorsal Root Ganglion Access and Injection in Swine. J. Vis. Exp. (2017)This video demonstrates a laminotomy procedure in an anesthetized pig to access the lumbar dorsal root ganglion for targeted neurotherapeutic delivery using convection-enhanced delivery.

Surgical Induction of Lumbar Spine Instability in Mouse Model: A Surgical Procedure for the Resection of the Lumbar Spinous Processes and Connected Ligaments in Murine Model

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2025

In this video, we describe the surgical procedure to induce lumbar spine instability in a mouse model by resecting the Lumbar L3 to L5 spinous process along with supraspinous and interspinous ligaments.

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