Maxillary Bone

The maxillary bone, or maxilla, is a paired facial bone that forms the upper jaw, supports the upper teeth, and contributes to the nasal cavity, orbit, and hard palate. Its structure combines compact and trabecular bone, while continuous remodeling by osteoblasts and osteoclasts adapts it to mechanical forces, tooth development, and changes in mineral demand. In biology and health research, the maxilla provides a model for studying craniofacial development, bone growth, dental support, and tissue repair. Understanding its anatomy and remodeling is also important in orthodontics, oral surgery, implant placement, and the treatment of maxillary fractures or congenital abnormalities.

Maxillary Bone - Related Videos

Research

JoVE Journal - Biology
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Methods for the Study of the Zebrafish Maxillary Barbel

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Cited by 7 •

2009

The zebrafish maxillary barbel is an integumentary sense organ containing ectodermal, mesodermal and neural crest derivatives. Importantly, the adult barbel can regenerate after proximal amputation. This video introduces maxillary barbel development and demonstrates a surgical protocol to induce regeneration, followed by collection, embedding and downstream imaging of barbel specimens.

Research

JoVE Journal - Medicine

Models of Bone Metastasis

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Cited by 115 •

2012

Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.

The Establishment of a Murine Maxillary Orthodontic Model

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2023

Here we demonstrate step-by-step a manageable, orthodontic tooth movement protocol operated on a murine maxillary model. With the explicit explanation of each step and visual demonstration, researchers can master this model and apply it to their experimental needs with a few modifications.

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Cited by 293 •

2016

Here we present a protocol for the dissection of hind limb long bones (femurs and tibiae) from the laboratory mouse. We further describe a rapid technique for bone marrow isolation from these bones that utilizes centrifugation for removal of bone marrow from the bone marrow space.

Bone Marrow Aspiration: A Method to Obtain Bone Marrow to Examine Cell Morphology

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2023

This video describes the technique of aspirating bone marrow from iliac spine and smear preparation for biopsy. In the example, we perform bone marrow aspiration from an acute myeloid leukemia (AML) patient and examine the cells to check for measurable residual disease (MRD), an important prognostic biomarker.

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