Osseointegrated Implant

An osseointegrated implant is a biomedical device that forms a direct, stable connection with living bone, providing structural support without an intervening layer of soft tissue. After placement, bone cells attach to and grow along the implant surface as healing tissue remodels, allowing mechanical loads to transfer between the skeleton and the device. This process supports dental restorations, joint replacements, and skeletal attachments for prosthetic limbs. By improving implant stability and function, osseointegration links materials science, bone biology, and regenerative medicine, while ongoing research seeks to optimize surface properties, healing, and long-term integration.

Osseointegrated Implant - Related Videos

Research

JoVE Journal - Biology
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Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

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Cited by 16 •

2009

There is a need to develop alternative prosthesis attachment due to limb loss attributed to vascular occlusive diseases and trauma. The goal of the work is to introduce an osseointegrated intelligent implant design system to increase skeletal fixation and reduce periprosthetic infection rates for patients needing osseointegrated technology.

Research

JoVE Journal - Biology
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Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

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2025

This study presents a novel surgical technique for implanting a biomimetic artificial intervertebral disc (BioAID). The method ensures precise placement and stability, aiming to restore cervical spine function using a goat model. This technique shows promise for clinical application in both human and canine patients suffering from cervical spine myelopathy.

Microbead Implantation in the Zebrafish Embryo

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Cited by 8 •

2015

The zebrafish is an excellent model system for genetic and developmental studies. Bead implantation is a valuable tissue manipulation technique that can be used to interrogate developmental mechanisms by introducing alterations in local cellular environments. This protocol describes how to perform microbead implantation in the zebrafish embryo.

Research

JoVE Journal - Medicine
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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

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Cited by 5 •

2012

Dual-chamber implantable cardioverter-defibrillators (ICDs) may improve detection of atrial fibrillation as well as differentiation of tachycardias. However, this advantage is undermined by complications associated with the second electrode, which is required in conventional dual chamber devices. Therefore, BIOTRONIK has developed a new electrode called the LinoxSMART S DX that, when used in conjunction with the Lumax DX ICD, offers dual-chamber detection without the risks associated with the...

Animal Model of Implant-Associated Infections in Mice

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2025

The present protocol describes a mouse model employing subcutaneous dorsal implantation to investigate implant-associated infections, enabling comprehensive investigation of pathophysiological mechanisms and supporting the development of diagnostic criteria with targeted therapeutic strategies.

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