Oviduct Embryos

Oviduct embryos are early-stage embryos that develop and travel through the oviduct, the reproductive tract connecting the ovary to the uterus. After fertilization, usually in the oviductal ampulla, the embryo undergoes cleavage while ciliary movement, smooth-muscle contractions, and oviductal secretions regulate its transport and provide a supportive microenvironment. Studying oviduct embryos helps researchers understand fertilization, preimplantation development, embryo–maternal communication, and the transition to the uterus, with applications in reproductive biology, assisted reproduction, developmental research, and animal breeding.

Oviduct Embryos - Related Videos

Research

JoVE EoE - Large Animal Models

Embryo Transfer Into Rabbit: A Procedure for Laparoscopy-Guided Transfer of Embryos Into Oviduct of Ovulating Recipient Female Rabbit Model

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2025

This video describes the technique of transferring embryos into the oviduct of a recipient female rabbit via Laparoscopy. It allows embryo remodeling in rabbits during its migration through the oviduct, eventually helping in successful implantation. This technique can also be used for stored embryos with good efficiency.

Alginate Hydrogels for Three-Dimensional Organ Culture of Ovaries and Oviducts

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Cited by 43 •

2011

Culture of normal cells in their three-dimensional context represents an alternative method to study early events required for cellular transformation and tumorigenesis. This method is used to grow normal ovarian and oviductal cells to study early events in ovarian cancer formation.

Research

JoVE Journal - Developmental Biology
Free Sample

Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis

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Cited by 17 •

2016

We present transient transgenesis and gene knockdown in Ciona intestinalis, a chordate sister group to vertebrates, using microinjection and electroporation techniques. Such methods facilitate functional genomics in this simple invertebrate that features rudimentary characteristics of vertebrates, including notochord and head sensory epithelia, and many orthologs of human disease associated genes.

Improved Genome Editing via Oviductal Nucleic Acids Delivery-based In Vivo Electroporation Technique for Knockout Mice Generation

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2025

The efficiency of the Improved Genome Editing via Oviductal Nucleic Acids Delivery (I-GONAD) method is comparable to traditional microinjection, which requires zygote collection from donor females and transfer to pseudo-pregnant females. This protocol demonstrates its effectiveness by introducing CRISPR/Cas9-induced mutations into the ROSA26 locus on chromosome 6.

Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos

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Cited by 2 •

2016

The goal of this protocol is to describe a loss- and gain-of function method that is applicable to identify neogenin as a stage-specific receptor that leads to trophectoderm and inner cell mass differentiation in preimplantation mouse embryos.

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