Parasympathetic Comparison

Parasympathetic comparison examines the parasympathetic division of the autonomic nervous system alongside other autonomic pathways, especially the sympathetic division, to clarify how the body regulates involuntary functions. Parasympathetic neurons arise from cranial and sacral regions, use acetylcholine at their synapses, and generally promote “rest-and-digest” responses by slowing heart rate, stimulating digestion, and supporting energy conservation. Comparing these pathways reveals how opposing and coordinated neural signals maintain homeostasis. This framework helps students and researchers interpret autonomic control in physiology, understand responses to stress and recovery, and analyze disorders or treatments that affect cardiovascular, gastrointestinal, and other organ systems.

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JoVE Core - Biology

The Parasympathetic Nervous System

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2019

Overview The parasympathetic nervous system is one of the two major divisions of the autonomic nervous system. This parasympathetic system is responsible for regulating many unconscious functions, such as heart rate and digestion. It is composed of neurons located in both the brain and the peripheral nervous system that send their axons to target muscles, organs, and glands. The “Rest and Digest” System Activation of the parasympathetic system tends to have a relaxing effect on the body,...

Parasympathetic Signaling

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2024

Parasympathetic signaling plays a crucial role in regulating various physiological processes. It involves the release of acetylcholine (ACh) by parasympathetic neurons, which can have localized and short-lived effects. The majority of ACh released is rapidly inactivated at the synapse by the enzyme acetylcholinesterase (AChE), which hydrolyzes Ach into choline and acetate. Additionally, the tissue cholinesterase deactivates any ACh diffusing into the surrounding tissues. The effects of...

Parasympathetic Division of the ANS

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2024

The parasympathetic division of the autonomic nervous system (ANS) regulates rest and digestion functions in the body. It works in opposition to the sympathetic division, promoting relaxation, conservation of energy, and digestion. The parasympathetic division consists of preganglionic fibers originating from specific cranial nerves (III, VII, IX, X) and the sacral spinal nerves (S2-S4). These fibers synapse with postganglionic neurons in the terminal ganglia, innervating various organs and...

Cranial Part of Parasympathetic Division

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2024

The cranial part of the parasympathetic division plays a crucial role in regulating the visceral functions of the head and specific structures in the neck, thoracic, and abdominopelvic cavities. Preganglionic fibers of the parasympathetic division exit the brain through cranial nerves III (oculomotor), VII (facial), IX (glossopharyngeal), and X (vagus), delivering parasympathetic output to the respective visceral structures. The vagus nerve (cranial nerve X) alone accounts for approximately 75...

The Sense of Self: Reflected Self-Appraisal and Social Comparison

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2020

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...

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