Renal Artery

The renal artery is a major blood vessel that carries oxygenated blood from the abdominal aorta to the kidneys, supporting filtration, metabolism, and tissue maintenance. After entering the kidney at the hilum, it branches into progressively smaller arteries that deliver blood to the renal cortex and medulla, where capillary networks surround nephrons and enable glomerular filtration. Renal artery blood flow therefore influences urine formation, fluid balance, and blood pressure regulation through the renin-angiotensin-aldosterone system. Studying renal artery anatomy and function is essential for understanding kidney physiology, diagnosing renal artery stenosis, and guiding vascular imaging, surgery, and treatment of hypertension.

Renal Artery - Related Videos

Research

JoVE Journal - Medicine
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Use of a Hanging-weight System for Isolated Renal Artery Occlusion

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Cited by 6 •

2011

A precise murine model for acute kidney injury (AKI) due to ischemia is an important tool to investigate acute kidney injury and possibly find therapeutic tools to treat renal injury. The hanging weight system offers a tool for immediate and reliable renal artery occlusion and reperfusion without causing renal congestion.

Research

JoVE Journal - Medicine
Free Sample

Direct Drug Delivery to Kidney via the Renal Artery

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2021

This manuscript describes a method for targeted delivery to a single kidney via a catheter placed in the infrarenal abdominal aorta in the mouse.

Research

JoVE EoE - Neuropathology

Sympathetic Denervation of Renal Arteries in an Angiotensin II-Induced Hypertension Mouse Model

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2025

This video demonstrates a procedure for renal artery sympathetic denervation in an angiotensin II-induced hypertensive mouse model, using phenol to disrupt sympathetic nerve function and reduce blood pressure.

Recording Changes in Renal Sympathetic Nerve Activity in Response to Arterial Pressure in Rats

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2025

This video demonstrates a technique of studying the activity of renal sympathetic nerves (RSNs) in response to changes in arterial pressure in rats. Upon attaching a pressure-sensing catheter to the femoral artery, the renal sympathetic nerves are exposed. The nerves are then lifted onto a recording electrode, and their electrical activity is recorded. Next, a vasoconstricting drug is injected to elevate blood pressure, and corresponding changes in RSN activity are monitored.

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches

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2025

This article presents a step-by-step protocol for the isolation and functional evaluation of human renal arterial branches, facilitating preclinical studies for pharmaceutical development.

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