Restraint Devices

Restraint devices are tools used to limit an animal’s movement in a controlled manner, supporting safe handling and reducing the risk of injury during biological research and veterinary procedures. They work through physical containment or positioning, with the device selected according to the animal’s species, size, behavior, and the procedure’s requirements; effective restraint limits unnecessary movement while allowing essential access. Applications include examination, sample collection, injection, treatment, and behavioral studies. Appropriate use improves experimental consistency, protects researchers and animals, and supports humane practices by minimizing stress and avoiding excessive force.

Restraint Devices - Related Videos

Education

JoVE Science Education - Basic Biology

Pig Handling and Restraint

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Acclimation and Positive Reinforcement Training Pigs are social animals that respond best to calm, low-stress handling techniques. Acclimation and positive reinforcement training are important refinement strategies recommended...

Rodent Handling and Restraint Techniques

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2015

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN It has been demonstrated that even minimal handling of mice and rats is stressful to the animals. Handling for cage changing and other noninvasive procedures causes an increase in heart rate, blood pressure, and other physiological parameters, such as serum corticosterone levels. Fluctuations can continue for up to several hours. The methods of restraint required for injections and blood...

Rabbit Handling and Manual Restraint

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Rabbits possess powerful hindlimb musculature and are susceptible to spinal injury if they struggle or kick while inadequately supported. Because rabbits vary in temperament and may struggle during restraint, handlers should...

Research

JoVE Journal - Biology
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Manual Restraint and Common Compound Administration Routes in Mice and Rats

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Cited by 95 •

2012

Working safely and humanely with research rodents requires a core competency in handling and restraint methods. This article will present the basic principles required to safely handle and effectively administer compounds to mice and rats.

Thermal Measurement Techniques in Analytical Microfluidic Devices

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Cited by 6 •

2015

Here, we present three protocols for thermal measurements in microfluidic devices.

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