Submandibular Ganglion
Submandibular Ganglion - Related Videos
05:18
Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct
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Cited by 17 •
2011
A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.
07:44
Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
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Cited by 5 •
2016
Salivary gland hypofunction, a major adverse effect of head and neck radiotherapy diminishes a patient's quality of life. The demonstration of efficacy of new therapies in animal models is a prerequisite before clinical transition. This protocol describes retroductal administration and local irradiation of rat submandibular glands.
04:41
Isolating Vestibular Ganglion Neurons From a Mouse Inner Ear
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2025
This video showcases a method for isolating vestibular neurons from a mouse pup's inner ear. It meticulously outlines the steps involved in dissecting the inner ear, harvesting the vestibular ganglion, and subsequently dissociating the ganglion into single cells. These cells are then cultured on glass-bottom dishes to establish a vestibular neuron culture.
07:45
Retroductal Nanoparticle Injection to the Murine Submandibular Gland
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Cited by 10 •
2018
Local drug delivery to the submandibular glands is of interest in understanding salivary gland biology and for the development of novel therapeutics. We present an updated and detailed retroductal injection protocol, designed to improve delivery accuracy and experimental reproducibility. The application presented herein is the delivery of polymeric nanoparticles.
05:26
Transfection of Mouse Retinal Ganglion Cells by in vivo Electroporation
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Cited by 5 •
2011
We demonstrate an in vivo electroporation protocol for transfecting single or small clusters of retinal ganglion cells (RGCs) and other retinal cell types in postnatal mice over a wide range of ages. The ability to label and genetically manipulate postnatal RGCs in vivo is a powerful tool for developmental studies.
FAQs
The synapse creates a functional boundary within the autonomic pathway. Signals arriving in preganglionic fibers are transferred to postganglionic neurons in the ganglion, which then send fibers onward to the target glands. This organization allows investigators to distinguish the central-to-ganglion segment from the ganglion-to-gland segment when interpreting cranial nerve anatomy.
Not every fiber associated with the ganglion forms a synaptic connection there. Sensory and sympathetic fibers may pass through without synapsing, so their presence does not identify them as the parasympathetic secretory relay. This distinction prevents anatomical tracing from assigning every fiber near the ganglion the same functional role.
The three structures represent successive anatomical associations rather than interchangeable nerves. The facial nerve carries the preganglionic pathway, the chorda tympani provides its route onward, and the lingual nerve carries those fibers to the ganglion. Mapping these transitions helps relate cranial nerve anatomy to the final glandular targets.
Following postganglionic fibers from the ganglion to both the submandibular and sublingual glands shows how one relay is linked with more than one glandular target. This arrangement provides an anatomical framework for studying salivary control and for distinguishing gland-directed pathways from fibers that merely traverse the region.
An effective tracing sequence begins at the superior salivatory nucleus, follows the preganglionic fibers with the facial nerve and chorda tympani, identifies their association with the lingual nerve, and then locates the synapse. The analysis can finally separate postganglionic fibers reaching the glands from nonsynapsing sensory or sympathetic fibers.
Because the pathway crosses several named structures before reaching the glands, conditions can be considered in relation to a specific segment rather than to salivation generally. Studying the ganglion therefore supports interpretation of conditions involving salivary function or the lingual nerve, while preserving the distinction between relay fibers and fibers passing through.