Thoracic Aorta

The thoracic aorta is the section of the body’s largest artery that extends from the heart through the chest, distributing oxygen-rich blood to the body and supplying branches that serve thoracic structures. Its elastic wall expands during ventricular contraction and recoils between beats, helping maintain continuous blood flow and stable arterial pressure as blood moves from the aortic arch toward the diaphragm. In biology and medicine, studying the thoracic aorta clarifies cardiovascular anatomy, hemodynamics, and vascular development. It also supports the diagnosis and management of conditions such as aneurysms, dissection, and atherosclerotic disease through imaging and physiological assessment.

Thoracic Aorta - Related Videos

Education

JoVE Core - Anatomy and Physiology

Thoracic Aorta

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2024

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...

Research

JoVE EoE - Large Animal Models

Porcine Aorta Isolation: A Surgical Procedure to Excise the Thoracic Aorta From Miniature Pigs for Downstream Analysis

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2025

In this video, we demonstrate a procedure for the surgical removal of the aorta from miniature pigs. Endothelial cells harvested from these isolated aortae can be further cultured in in vitro conditions to study coagulation and immune responses.

Research

JoVE Journal - Medicine
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Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions

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Cited by 39 •

2019

Ultrasound imaging has become a common modality to determine the luminal dimensions of thoracic and abdominal aortic aneurysms in mice. This protocol describes the procedure to acquire reliable and reproducible two-dimensional ultrasound images of the ascending and abdominal aorta in mice.

Measurement of Endothelium-Dependent Vasorelaxation in the Mouse Thoracic Aorta Using Tensometric Small Volume Chamber Myography

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Cited by 1 •

2022

The present protocol describes the concepts and technical application of the tensometric myograph technique using a multi-chamber myograph system in the experimental ex vivo assessment of mouse aortic endothelial function.

Flow Cytometry Analysis of Immune Cells Within Murine Aortas

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Cited by 87 •

2011

This paper presents a flow cytometry-based method to investigate the immune composition of aortas. The paper also illustrates an additional technique that allows examining surrounding adventitia and vessel wall separately. This method opens possibilities to perform phenotypical analyses of aortic leukocytes and apply several immunological assays for atherosclerosis studies.

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