Breast Cancer Surgery
Breast Cancer Surgery - Related Videos
11:49
Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
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2026
This study describes a standardized surgical procedure for single-port endoscopic axillary lymph node dissection without liposuction in breast cancer. Indicated for patients with biopsy-confirmed nodal metastasis or positive sentinel lymph nodes, the technique emphasizes preservation of critical structures, particularly the intercostobrachial nerve, to reduce postoperative morbidity and optimize functional recovery.
03:07
Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
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2025
This prospective study evaluated the implementation of a novel, single-port, robotic platform in oncoplastic breast-conserving surgery for malignant lesions. The primary endpoint focused on technical success, defined as the achievement of tumor-free resection margins confirmed by intraoperative frozen-section histopathology, with secondary assessment of aesthetic outcomes and life quality score of patients.
10:10
Long-term Culture of Human Breast Cancer Specimens and Their Analysis Using Optical Projection Tomography
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Cited by 11 •
2011
We have developed a collagen-based in vitro assay which promotes proliferation and invasion from samples of all breast cancer subtypes. Optical Projection Tomography, a three dimensional microscopy technique was utilised to visualise and quantify tumour expansion. This assay may be used to quantify drug response of individual tumour samples.
07:13
Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
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Cited by 27 •
2014
Activation of latent mutations with adenovirus-Cre into the mammary ductal system results in a clinically relevant metastatic breast cancer. Incorporation of a YFP promoter allows tracking of distal metastatic tumor cells. This model is useful to study latent metastasis, anti-tumor immunity, and for designing novel immunotherapies to treat breast cancer.
07:47
Studying the Role of Alveolar Macrophages in Breast Cancer Metastasis
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Cited by 7 •
2016
Here we describe the model and approach to study functions of pulmonary alveolar macrophages in cancer metastasis. To demonstrate the role of these cells in metastasis, the syngeneic (4T1) model of breast cancer in conjunction with the depletion of alveolar macrophage with clodronate liposomes was used.
FAQs
Surrounding margins provide tissue beyond the visible breast tumor for surgical and pathological assessment. Examining these margins helps determine whether malignant tissue extends beyond the primary lesion and contributes to treatment planning. The findings can influence decisions about additional local treatment, radiation, or systemic therapy by clarifying the extent of disease.
Both approaches assess whether breast cancer has spread to regional lymph nodes, but they examine lymphatic disease at different surgical scopes. Sentinel lymph node biopsy evaluates selected regional nodes, whereas axillary lymph node surgery addresses lymph nodes in the axilla. Their findings contribute to staging and help guide subsequent cancer treatment.
Neoadjuvant treatment is part of the evolving approach to managing breast cancer around the time of surgery, while pathology examines tissue removed during the operation. Together with surgical findings, these assessments help evaluate treatment response and characterize disease extent. That information supports decisions about radiation, systemic therapy, and further cancer management.
Imaging advances can improve how clinicians assess breast tumors before or around an operation, while oncoplastic techniques combine tumor removal with approaches intended to preserve or restore breast structure. In cancer research, these developments are evaluated for their ability to maintain cancer control while improving surgical results and supporting quality of life.
After surgery, clinicians use the removed tumor, surrounding margins, and any sampled lymph nodes for pathological evaluation. These findings help establish tumor stage, assess regional spread, and determine whether the operation achieved the intended tissue removal. The resulting information guides decisions about radiation and systemic therapy and helps evaluate response to prior treatment.
Less invasive approaches are relevant when researchers seek to reduce complications without weakening cancer treatment. Their evaluation occurs alongside advances in imaging, surgical technique, and treatment sequencing. Research outcomes include cancer control, the extent of tissue removal, treatment response, postoperative effects, and the preservation or restoration of breast structure and quality of life.