Scalable Fabrication

Scalable fabrication is the engineering design of manufacturing processes that can increase production volume while maintaining consistent quality, performance, and cost efficiency. It relies on principles such as process standardization, modular system design, automation, and controlled operating conditions to transfer a prototype or laboratory method into repeatable production. Engineers use scalable fabrication to produce materials, devices, components, and structures across larger batches or areas, often by improving throughput, resource use, and process reliability. This approach supports the development of technologies that must move from experimental demonstrations to practical deployment, including advanced materials, electronics, biomedical devices, and energy systems.

Scalable Fabrication - Related Videos

Research

JoVE Journal - Bioengineering

A Simple and Scalable Fabrication Method for Organic Electronic Devices on Textiles

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Cited by 1 •

2017

In this paper, we present a protocol to selectively deposit organic materials on textiles, which allows for the direct integration of organic electronic devices with wearables. The fabricated devices can be fully integrated in textiles, respecting their mechanical appearance and enabling sensing capabilities.

Scalable Solution-processed Fabrication Strategy for High-performance, Flexible, Transparent Electrodes with Embedded Metal Mesh

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Cited by 3 •

2017

This protocol describes a solution-based fabrication strategy for high-performance, flexible, transparent electrodes with fully-embedded, thick metal mesh. Flexible transparent electrodes fabricated by this process demonstrate among the highest reported performances, including ultra-low sheet resistance, high optical transmittance, mechanical stability under bending, strong substrate adhesion, surface smoothness, and environmental stability.

Scalable Stamp Printing and Fabrication of Hemiwicking Surfaces

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Cited by 4 •

2018

A simple protocol is provided for the fabrication of hemiwicking structures of varying sizes, shapes, and materials. The protocol uses a combination of physical stamping, PDMS molding, and thin-film surface modifications via common materials deposition techniques.

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

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Cited by 43 •

2018

Here, we present a protocol that describes the fabrication of stretchable, dual channel, organ chip microfluidic cell culture devices for recapitulating organ-level functionality in vitro.

Research

JoVE Journal - Developmental Biology
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Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

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Cited by 23 •

2015

The protocols described allow laboratories to perform scalable, adherent stem cell culture in high throughput with minimal labor, experience and equipment investment cost using a programmable liquid handling robot and 96-well plates. iPSCs passaged more than 20 times on this system maintained pluripotency, normal karyotypes and differentiated into cardiomyocytes.

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