Conjunctival Hyperemia

Conjunctival hyperemia is the visible reddening of the conjunctiva caused by increased blood flow in its superficial vessels, making it an important clinical sign of ocular surface disturbance. In immunology and infection, inflammatory mediators released in response to pathogens, allergens, or irritation promote vasodilation and vascular permeability, producing redness that may accompany swelling, discharge, or discomfort. Assessing the distribution and severity of hyperemia helps clinicians evaluate conjunctival inflammation, monitor disease progression, and support differential diagnosis alongside other findings. It also provides a readily observable outcome in studies of host responses, ocular infections, and anti-inflammatory treatments.

Conjunctival Hyperemia - Related Videos

Research

JoVE Journal - Medicine

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

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2022

The present protocol describes the cross-sectional research performed on 40 healthy subjects between the ages of 20 and 45 to assess the prevalence of dry eye syndrome (DES) during COVID-19. The OSDI survey evaluated DES, and the advanced ophthalmic systems (AOS) software was used to assess limbal redness.

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

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2025

Here, we present a protocol for harvesting and processing conjunctival biopsy to identify mucous membrane pemphigoid.

Swab-based Conjunctival Commensal Bacteria Isolation: A Technique to Isolate Commensal Bacteria from Conjunctiva of Murine Model

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2025

This video describes a swab-based technique to isolate viable commensal bacteria from the ocular conjunctiva. The technique can be used to profile the commensal bacterial microbiome of the conjunctiva, which plays a defensive role against pathogens.

Conjunctival Commensal Isolation and Identification in Mice

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2021

Presented here is a protocol for the isolation and amplification of aerobic and facultative anaerobic mouse conjunctival commensal bacteria using a unique eye swab and culture-based enrichment step with subsequent identification by microbiological based methods and MALDI-TOF mass spectrometry.

Near-Infrared Spectroscopy During Reactive Hyperemia for the Assessment of Lower Limb Vascular Function

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Cited by 3 •

2024

Here, we describe a non-invasive approach using near-infrared spectroscopy to assess reactive hyperemia in the lower limb. This protocol provides a standardized assessment of vascular and microvascular responsiveness that may be used to determine the presence of vascular dysfunction as well as the efficacy of therapeutic interventions.

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