Paramagnetic Solution
Paramagnetic Solution - Related Videos
11:07
Electron Paramagnetic Resonance (EPR) Spectroscopy
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2023
Source: David C. Powers, Tamara M. Powers, Texas A&M In this video, we will learn the basic principles behind Electron Paramagnetic Resonance (EPR). We will use EPR spectroscopy to study how dibutylhydroxy toluene (BHT) behaves as an antioxidant in the autoxidation of aliphatic aldehydes.
01:30
Paramagnetism
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2023
Paramagnets are materials with unpaired electrons that possess a finite magnetic moment. In the absence of a magnetic field, these moments are randomly oriented, and thus the net moment is zero. Under an external field, a torque acting on the moments tends to align them along the field's direction. However, the random thermal motion of electrons produces a torque opposite to the external field and tries to disorient the moments. These two competing effects align only a few moments along the...
08:01
Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
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Cited by 11 •
2016
A new electron paramagnetic resonance (EPR) method, rapid scan EPR (RS-EPR), is demonstrated for 2D spectral spatial imaging which is superior to the traditional continuous wave (CW) technique and opens new venues for in vivo imaging. Results are demonstrated at 250 MHz, but the technique is applicable at any frequency.
07:27
Making Solutions in the Laboratory
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2023
The ability to successfully make solutions is a basic laboratory skill performed in virtually all biological and chemical experiments. A solution is a homogenous mixture of solute dissolved in bulk liquid known as the solvent. Solutions can be described by their solute concentration, a measure of how much solute is present per unit of solution. In this video, a step-by-step procedure for how to make a water-based, or aqueous, solution for biological applications is presented. The video...
09:49
Solutions and Concentrations
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2023
Source: Laboratory of Dr. Michael Evans — Georgia Institute of Technology A solution is a homogeneous mixture containing some components in small amounts, called solutes, and one component in a large amount, called the solvent. Solid-liquid solutions contain one or more solid solutes dissolved in a liquid solvent. Solutions are ubiquitous in chemistry: they are used to store and handle small amounts of material, carry out chemical reactions, and develop materials with controllable properties.
FAQs
Selectivity comes from the interaction between the coating and a matching target. Antibodies or other binding molecules can recognize particular cells, microorganisms, proteins, or nucleic acids within a complex specimen. Once the intended target is bound, magnetic handling separates that target-bearing fraction from surrounding sample components, supporting more focused downstream analysis in immunology and infection research.
Particles that lose most or all of their magnetism after field removal can be handled without remaining permanently magnetized. This temporary response allows the applied field to collect target-associated particles during separation while limiting persistent magnetic behavior afterward. That property supports practical sample processing when researchers need to isolate material and continue with later analytical steps.
The same magnetic principle can support different research goals depending on what the particles bind. Cell-directed particles enable immunomagnetic cell separation, whereas particles directed toward microorganisms support pathogen enrichment. Binding molecules aimed at proteins or nucleic acids instead support molecular sample preparation. Thus, target recognition determines which fraction is recovered and what analysis follows.
Recovery depends primarily on whether the particle coating can recognize and bind the intended target in the specimen. The composition and complexity of the sample also matter because surrounding material can accompany or remain separate from the captured fraction. These relationships influence the usefulness of the separated material for subsequent cell, pathogen, protein, nucleic acid, or diagnostic analysis.
A typical workflow combines the particle suspension with the biological sample so the selected binding molecules can capture their targets. Applying a magnetic field then separates the target-associated particles from the surrounding material. The recovered fraction can proceed to analysis or further preparation. The exact target and binding molecule determine whether the workflow addresses cells, microorganisms, proteins, or nucleic acids.
Researchers may choose magnetic handling when they need to enrich a pathogen, isolate a selected biological component, or prepare a complex specimen for diagnostic analysis. In infection research, target-specific capture can concentrate microorganisms or relevant proteins and nucleic acids before measurement. This helps connect molecular recognition with physical separation and can make subsequent examination more focused.
Separated fractions provide material in which the selected target has been captured relative to the original surrounding sample. Depending on the binding molecule, the fraction may contain immune-related cells, microorganisms, proteins, or nucleic acids. Researchers can then use that prepared material in analytical or diagnostic workflows, making the magnetic step a bridge between specimen complexity and targeted investigation.