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Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
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1Department of Chemistry and Biochemistry,University of Denver, 2Magnetic Imaging Group, Applied Physics Division, Physical Measurements Laboratory,National Institute of Standards and Technology, 3Department of Radiology, Geisel School of Medicine,Dartmouth University, 4Department of Biochemistry,West Virginia University, 5Department of Electrical and Computer Engineering,University of Denver, 6Department of Engineering,University of Denver
Chapters
- 00:05Title
- 00:58Setup of the Rapid Scan Coil Driver at 250 MHz
- 02:01Preparation of Reagents and Phantoms
- 03:17Setup of the Rapid Scan Instrument at 250 MHz
- 05:58Results: 2D RS-EPRI Phantom Images
- 07:12Conclusion
A new electron paramagnetic resonance (EPR) method, rapid scan EPR (RS-EPR), is demonstrated for 2D spectral spatial imaging which is superior to the traditional continuous wave (CW) technique and opens new venues for in vivo imaging. Results are demonstrated at 250 MHz, but the technique is applicable at any frequency.
Tags
Keywords:
Rapid-scan EPR ImagingRSEPRIElectron Paramagnetic ResonanceOxygen ConcentrationPHRedox StatusSignaling MoleculesBiomedical ResearchCancer ResearchTumor EnvironmentContinuous Wave EPRRapid-scan Experimental ConditionsResonator BandwidthRapid-scan Coil DriverN-15 PDTBMPOHydrogen PeroxideUV Irradiation
