Alexis Wound Retractor

The Alexis Wound Retractor is a sterile surgical device that provides circumferential access to an incision while protecting the wound edges during an operation. It uses two flexible rings connected by a transparent polymer membrane: the inner ring is placed inside the incision, while the outer ring is rolled outward to create gentle, even tension that holds tissue aside and forms a barrier over the wound margins. This design supports visualization and instrument access in open and minimally invasive procedures, helps limit direct contact between instruments and tissue, and can reduce exposure to contamination and mechanical trauma, contributing to safer, more controlled surgical handling.

Alexis Wound Retractor - Related Videos

Research

JoVE Journal - Medicine

Demonstration of the Rat Ischemic Skin Wound Model

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Cited by 32 •

2015

The rat, due to its size, availability, and rather docile behavior, has been utilized as a research model for many years. The goal of this protocol is to utilize the rat as an ischemic skin wound healing model to provide valuable insight into the pathophysiology of chronic wounds.

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

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Cited by 6 •

2012

This article provides a detailed and visual description of a methodology for collecting and measuring biochemical inflammatory and nociceptive mediators at the surgical wound site following cesarean delivery. This human bioassay has been used to determine correlations between wound and serum cytokine concentrations and drug-mediated changes in wound cytokines, chemokines and neuropetides.

Murine Model of Wound Healing

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Cited by 207 •

2013

A murine model of cutaneous wound healing that can be used to assess therapeutic compounds in physiological and pathophysiological settings.

Research

JoVE Journal - Bioengineering
Free Sample

Microinjection Wound Assay and In vivo Localization of Epidermal Wound Response Reporters in Drosophila Embryos.

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Cited by 10 •

2013

The embryonic epidermis of very late stage Drosophila embryos provides an in vivo system for rapid puncture wound response analysis and can be combined with genetic manipulations or chemical microinjection treatments to advance studies in wound healing for translation into mammalian models.

Swine Model of Biofilm Infection and Invisible Wounds

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Cited by 12 •

2023

Chronic wounds that are resistant to antibiotics are a major threat to the healthcare system. Biofilm infections are stubborn and hostile and can cause deficient functional wound closure. We report a clinically relevant swine model of biofilm-infected full-thickness chronic wounds. This model is powerful for mechanistic studies as well as for testing interventions.

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