Aortic Injury Surgery
Aortic Injury Surgery - Related Videos
08:33
Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model
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Cited by 5 •
2016
Understanding the cellular and molecular mechanisms of re-endothelialization following arterial denudation injury is of paramount importance in preventing thrombosis and restenosis of arteries. Here we describe a protocol for reproducible arterial denudation injury of the infrarenal abdominal aorta. The procedure was developed to investigate the underlying mechanisms that regulate endothelial regeneration using mouse models.
06:50
A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
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Cited by 1 •
2025
This study describes a model of acute lung injury following visceral ischemia-reperfusion during supra-celiac aortic cross-clamping via laparotomy in rats. It enables the investigation of both the clinical and biological effects of aortic clamping as well as the impact of ischemia-reperfusion on underlying organs and remote lung injuries.
06:14
Murine Aortic Crush Injury: An Efficient In Vivo Model of Smooth Muscle Cell Proliferation and Endothelial Function
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Cited by 2 •
2017
Restenosis following cardiovascular procedures (bypass surgery, angioplasty, or stenting) is a significant problem reducing the durability of these procedures. An ideal therapy would inhibit smooth muscle cell (VSMC) proliferation while promoting regeneration of the endothelium. We describe a model for simultaneous assessment of VSMC proliferation and endothelial function in vivo.
07:32
Murine Flexor Tendon Injury and Repair Surgery
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Cited by 45 •
2016
Flexor tendons in the hand are commonly injured, leading to impaired hand function. However, the scar-tissue healing response is not well characterized. A murine model of flexor tendon healing is demonstrated here. This model can enhance overall understanding of the healing process and assess therapeutic approaches to improve healing.
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
FAQs
The damaged segment’s location and extent help determine whether surgeons repair it directly, replace part of the vessel, or seal it from inside with an endovascular stent graft. These factors are considered alongside hemodynamic stability and associated organ damage, because the chosen strategy must control bleeding while preserving adequate blood flow to affected tissues.
Hemodynamic stability indicates how urgently blood loss and circulation must be controlled. A patient’s stability, combined with the injury pattern and other organ damage, influences the balance between open surgery and an endovascular approach. This assessment helps clinicians select a treatment capable of restoring vessel integrity while addressing immediate threats such as rupture or severe blood loss.
An endovascular stent graft is deployed within the aorta to seal the injured area from inside the vessel. By covering the damaged segment, it can help control bleeding while maintaining a pathway for blood flow through the aorta. This mechanism differs from open repair, which manages the affected vessel segment directly through surgery.
Management centers on controlling bleeding, restoring the aorta’s structural integrity, and preserving blood flow. Depending on the injury, the damaged segment may be repaired or replaced during open surgery, or sealed internally with a stent graft. Imaging and assessment of stability, injury extent, location, and organ damage help shape the selected procedure.
The choice between open and endovascular treatment depends on the injury’s location and extent, the patient’s hemodynamic stability, and associated organ damage. Open surgery directly addresses the damaged segment and may involve repair or replacement, whereas endovascular treatment seals it internally. These considerations allow the operative plan to match the injury and the patient’s condition.
Successful treatment can restore vessel integrity and blood flow while reducing the dangers associated with ongoing aortic damage. Timely intervention may help prevent rupture, ischemia, and life-threatening blood loss. In medical practice, advances in imaging and minimally invasive repair have supported continued improvement in how clinicians evaluate and treat these injuries.