Bilstm-crf

BiLSTM-CRF is a sequence-labeling method that combines a bidirectional long short-term memory network with a conditional random field to assign structured labels to tokens in text. The BiLSTM reads a sequence from both directions, capturing preceding and following context, while the CRF scores transitions between neighboring labels and selects the most probable label path, often using Viterbi decoding. In medicine, this architecture supports biomedical named entity recognition and clinical information extraction, such as identifying diseases, medications, symptoms, and other clinically relevant terms, helping process electronic health records and biomedical literature more consistently.

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Research

JoVE Journal - Biology

An Analytical Tool that Quantifies Cellular Morphology Changes from Three-dimensional Fluorescence Images

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Cited by 4 •

2012

We developed a software platform that utilizes Imaris Neuroscience, ImarisXT and MATLAB to measure the changes in morphology of an undefined shape taken from three-dimensional confocal fluorescence of single cells. This novel approach can be used to quantify changes in cell shape following receptor activation and therefore represents a possible additional tool for drug discovery.

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