Noninvasive Ultrasound

Noninvasive ultrasound is a medical imaging technique that uses high-frequency sound waves to visualize internal organs, tissues, and blood flow without incisions or ionizing radiation. A transducer sends sound pulses into the body and converts returning echoes into images; differences in acoustic impedance determine how structures appear, while Doppler processing measures the movement of blood. Clinicians use ultrasound for diagnosis, pregnancy monitoring, cardiovascular assessment, and guidance of procedures such as needle placement. Its portability, real-time imaging, and favorable safety profile support repeated examinations and point-of-care care, while advances in three-dimensional imaging and elastography continue to expand its clinical and research applications.

Noninvasive Ultrasound - Related Videos

Education

JoVE Science Education - Engineering

Noninvasive Blood Pressure Measurement Techniques

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2023

Source: Hamna J. Qureshi and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana Here we will highlight the key similarities and differences of noninvasive blood pressure measurement techniques between humans and rodents and examine the engineering principles that govern blood pressure. The principles that govern current cuff technology to acquire systolic and diastolic pressures will also be discussed. Commercially available cuffs that connect...

High-frequency Ultrasound Imaging of the Abdominal Aorta

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2023

Source: Amelia R. Adelsperger, Evan H. Phillips, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana High-frequency ultrasound systems are used to acquire high resolution images. Here, the use of a state-of-the-art system will be demonstrated to image the morphology and hemodynamics of small pulsatile arteries and veins found in mice and rats. Ultrasound is a relatively inexpensive, portable, and versatile method for the noninvasive...

Research

JoVE Journal - Neuroscience

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

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Cited by 4 •

2023

This work demonstrates the use of a multimodal ultrasound-based imaging platform for noninvasive imaging of ischemic stroke. This system allows for the quantification of blood oxygenation through photoacoustic imaging and impaired perfusion in the brain through acoustic angiography.

Ophthalmic Drug Delivery for Noninvasive Neuromodulation in a Mouse Model

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2025

Source: Zhan, J., et al. Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity. J. Vis. Exp. (2019)This video demonstrates a non-invasive ophthalmic drug delivery method for targeted neuromodulation. The drug is delivered via eye drops, absorbed into the circulation, crosses the blood-brain barrier, and activates specific neuronal receptors.

Research

JoVE Journal - Medicine
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A Novel Application of Musculoskeletal Ultrasound Imaging

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Cited by 14 •

2013

We describe a new ultrasound-based vector tissue Doppler imaging technique to measure muscle contraction velocity, strain and strain rate with sub-millisecond temporal resolution during dynamic activities. This approach provides complementary measurements of dynamic muscle function and could lead to a better understanding of mechanisms underlying musculoskeletal disorders.

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