Polymethyl Methacrylate

Polymethyl methacrylate (PMMA) is a transparent acrylic thermoplastic used in medicine because it combines light weight, rigidity, optical clarity, and moldability. It forms when methyl methacrylate monomers undergo free-radical polymerization, producing a solid polymer whose properties depend on formulation, curing conditions, and processing. In clinical practice, PMMA serves as bone cement for securing joint implants through mechanical interlock, and it is used in dentures, cranial repair materials, and intraocular lenses. Its tunable structure and established processing methods support applications in orthopedic, dental, ophthalmic, and reconstructive medicine, while ongoing research examines improved strength, biocompatibility, and delivery performance.

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Research

JoVE Journal - Chemistry

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

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Cited by 9 •

2016

A method for the atom transfer radical polymerization of functionalized vinyl monomers using perylene as a visible-light photocatalyst is described.

Fabrication and Characterization of Disordered Polymer Optical Fibers for Transverse Anderson Localization of Light

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Cited by 17 •

2013

We develop and characterize a disordered polymer optical fiber that uses transverse Anderson localization as a novel waveguiding mechanism. This microstructured fiber can transport a small localized beam with a radius that is comparable to the beam radius of conventional optical fibers.

Research

JoVE Journal - Behavior
Free Sample

Establishment of a Valuable Mimic of Alzheimer's Disease in Rat Animal Model by Intracerebroventricular Injection of Composited Amyloid Beta Protein

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Cited by 15 •

2018

This is a protocol to mimic Alzheimer's Disease in rats by evaluation of spatial memory impairment, neuronal pathological changes, neuronal amyloid beta protein (Aβ) burden, and neurofibrillary tangles aggregation, induced by the injection of Aβ25-35 combined with aluminum trichloride and recombinant human transforming growth factor-β1.

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

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Cited by 37 •

2017

We provide a generalized protocol based on a microfluidic bioprinting strategy for engineering a microfibrous vascular bed, where a secondary cell type could be further seeded into the interstitial space of this microfibrous structure to generate vascularized tissues and organoids.

Research

JoVE Journal - Engineering
Free Sample

Prescribed 3-D Direct Writing of Suspended Micron/Sub-micron Scale Fiber Structures via a Robotic Dispensing System

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Cited by 6 •

2015

Here, we present a protocol to fabricate freely-suspended, micron/sub-micron scale polymer fibers and “web-like” structures generated via automated direct writing procedure by means of a 3-axis dispensing system.

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