Prisma 2020
Prisma 2020 - Related Videos
01:27
Systematic Reviews
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2026
A systematic review is a rigorous, transparent method for identifying, evaluating, and combining all relevant research to address a specific question. For instance, a review might examine whether exercise reduces anxiety. Unlike narrative reviews, systematic reviews follow predefined protocols to reduce bias and ensure comprehensive coverage of the available evidence. Many follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, which include...
06:50
Wide-Field, Real-Time Imaging of Local and Systemic Wound Signals in Arabidopsis
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Cited by 7 •
2021
Extracellular glutamate-triggered systemic calcium signaling is critical for the induction of plant defense responses to mechanical wounding and herbivore attack in plants. This article describes a method to visualize the spatial and temporal dynamics of both these factors using Arabidopsis thaliana plants expressing calcium- and glutamate-sensitive fluorescent biosensors.
07:13
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
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Cited by 1 •
2025
This study evaluates prognostic systems for colorectal signet-ring cell carcinoma patients using machine learning models and competing risk analyses. It identifies log odds of positive lymph nodes as a superior predictor compared to pN staging, demonstrating strong predictive performance and aiding clinical decision-making through robust survival prediction tools.
08:15
Innovative Strategies for Organ Preservation in Heart Transplantation: Uniform Cooling Preservation and Ex-situ Normothermic Perfusion
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2025
Donor heart preservation is a major determinant of success in heart transplantation. Technological advances have led to optimizing the conditions of preservation, along with a more accurate assessment of the donor heart before transplantation. We herein describe two innovative technologies currently applied for cardiac preservation: uniform cooling preservation and normothermic ex-situ heart perfusion.
07:41
Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
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Cited by 2 •
2022
We present a protocol to induce and phenotype an acute right heart failure in a large animal model with chronic pulmonary hypertension. This model can be used to test therapeutic interventions, to develop right heart metrics or to improve the understanding of acute right heart failure pathophysiology.
FAQs
PRISMA 2020 improves reporting by making the review's methods and findings easier to inspect and compare. Its checklist gives authors a consistent structure for explaining how evidence was identified, evaluated, and combined. This reduces ambiguity in published medical evidence and helps readers judge whether the conclusions are adequately supported.
They provide a visual account of records identified, excluded, and included during the review process. By showing these stages in sequence, the diagrams make study selection easier to follow and reveal how the final evidence base was formed. In medicine, this supports clearer interpretation of the evidence underlying a synthesis.
Critical appraisal depends on enough detail to examine the review question, eligibility criteria, information sources, search strategy, data collection, risk-of-bias assessment, and synthesis. PRISMA 2020 brings these elements into a single reporting structure, allowing readers to identify where judgments entered the review and to assess the reliability of its conclusions.
Authors can use the 27-item checklist to organize reporting from the review question through the synthesis and results. They should also use the corresponding flow diagram to document records identified, excluded, and included. Applying these tools during manuscript preparation helps present methods and findings completely and consistently for medical readers.
A report should make explicit its eligibility criteria, information sources, search strategy, data collection, risk-of-bias assessment, and synthesis methods. It should also show how records moved through identification, exclusion, and inclusion. These details let readers trace the review's process, understand how evidence entered the analysis, and evaluate the resulting synthesis.
Transparent reporting helps clinicians and other healthcare decision-makers understand how synthesized evidence was assembled and how much confidence to place in its conclusions. By reducing reporting ambiguity and supporting critical appraisal, the guideline improves the clinical usefulness of systematic reviews and meta-analyses. Its value therefore extends beyond publication quality to the interpretation and application of medical evidence.