Transient Ischemic Attack

Transient ischemic attack (TIA) is a brief episode of focal neurological dysfunction caused by temporary interruption of blood flow to the brain, spinal cord, or retina, without persistent tissue infarction. It occurs when an embolus, atherosclerotic narrowing, or another vascular disturbance reduces perfusion, producing sudden symptoms such as weakness, numbness, speech difficulty, or vision loss that typically resolve. Although symptoms disappear, a TIA is a medical warning of elevated stroke risk and requires urgent assessment with neurological examination, brain and vascular imaging, and evaluation for cardiac sources. Identifying the cause supports preventive treatment, including risk-factor control and appropriate antithrombotic therapy.

Transient Ischemic Attack - Related Videos

Education

JoVE Core - Pathophysiology

Transient Ischemic Attack l: Introduction

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2026

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

Acid Attack on Concrete

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2024

When acids come into contact with concrete, they initiate a chemical reaction that dissolves the hydrated cement paste. This process leads to softening and structural weakening of the concrete. This issue is commonly observed in environments such as chimneys, sewers, and industrial settings. The severity of the damage increases as the pH of the water interacting with the concrete drops below 6.5. In particular, a pH under 4.5 can cause significant concrete damage. The rate at which hydrogen...

Selecting Competitors to Attack or Avoid

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2024

In competitive marketing, companies strategically decide which competitors to challenge or avoid based on market share, product offerings, and operational efficiency. Attacking a competitor involves identifying exploitable weaknesses, such as poor customer service, outdated products, or inefficient processes. Smaller companies often successfully challenge larger firms by leveraging their agility, offering more responsive customer support or faster innovation cycles. For example, ride-sharing...

Sulfate Attack on Concrete

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2024

Sulfate attack on concrete is a deterioration process characterized by a whitish discoloration beginning at the edges and corners, accompanied by cracking and spalling. This phenomenon occurs when sulfates react with the components of hardened concrete, forming compounds like calcium sulfate and calcium sulfoaluminate which occupy more space than the substances they replace, causing the concrete to expand and disrupt. Sulfates from sources like soil, groundwater, or industrial effluents...

Research

JoVE Journal - Medicine

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

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Cited by 15 •

2020

Here, we describe a mouse model of retinal ischemia by transient bilateral common carotid artery occlusion using simple sutures and a clamp. This model can be useful for understanding the pathological mechanisms of retinal ischemia caused by cardiovascular abnormalities.

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