Uterine Rupture

Uterine rupture is a rare but life-threatening obstetric complication in which the uterine wall tears, most often during late pregnancy or labor, and requires immediate medical intervention. The tear can develop when contractions and mechanical stress exceed the strength of the myometrium, particularly at a previous cesarean or other uterine surgical scar, allowing the fetus or placenta to extend beyond the uterine cavity and causing severe internal bleeding. Rapid recognition of abnormal fetal heart patterns, sudden abdominal pain, maternal shock, or loss of fetal station supports emergency delivery and surgical repair or hysterectomy. Understanding uterine rupture guides risk assessment, labor monitoring, counseling, and prevention in high-risk pregnancies.

Uterine Rupture - Related Videos

Research

JoVE Journal - Medicine

Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue

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Cited by 62 •

2012

A description of the surgical induction of endometriosis in mice and rats by auto-transplantation of uterine tissue to the arterial cascade of the intestinal mesentery.

Education

JoVE Core - Anatomy and Physiology

Uterine Tubes

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2024

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...

Research

JoVE Journal - Immunology and Infection
Free Sample

Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens

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Cited by 22 •

2013

We describe a method for tracking the endomembrane rupture elicited by the intracellular bacteria Shigella flexneri and Mycobacterium tuberculosis upon host cell invasion. Our assay makes use of CCF4, a host cytoplasmic FRET probe in live or fixed cells. This reporter is degraded by an enzyme activity present on the bacterial surface.

Research

JoVE Journal - Medicine
Free Sample

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

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2025

Here, we introduce a novel approach-Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri. A laparoscopic extracorporeal knot-pusher is used to perform cervical cerclage, achieving complete occlusion of uterine arteries. Thereafter, the corpus uteri are excised to enhance visibility and facilitate the operative field.

A Photodynamic Approach to Study Function of Intracellular Vesicle Rupture

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2023

AlPcS2a-mediated chromophore-assisted laser inactivation (CALI) is a powerful tool for studying spatiotemporal damage of intracellular vesicles (IVs) in live cells.

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