Acute Brainstem Infarction

Acute brainstem infarction is an ischemic stroke in which interrupted blood flow damages tissue in the brainstem, a region that regulates vital functions and connects the brain with the spinal cord. It commonly results from occlusion of arteries in the vertebrobasilar circulation or their small penetrating branches; oxygen deprivation rapidly disrupts neuronal signaling and can produce cranial-nerve deficits, weakness, impaired coordination, altered consciousness, or respiratory and cardiovascular instability. In neuroscience and clinical research, studying this emergency supports rapid recognition, neuroimaging, vascular assessment, and timely treatment while clarifying brainstem circuitry, predicting recovery, and guiding rehabilitation after injury.

Acute Brainstem Infarction - Related Videos

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JoVE Journal - Medicine

Acute Myocardial Infarction in Rats

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Cited by 103 •

2011

The rat model of acute myocardial infarction (AMI) is useful to study the consequence of a MI on cardiac pathophysiological and physiological function.

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

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Cited by 13 •

2016

Reliable and accurate outcome assessment is the key for translation of preclinical therapies into clinical treatment. The current paper describes how to assess three clinically relevant primary outcome parameters of cardiac performance and damage in a pig acute myocardial infarction model.

Inducing Acute Pons Infarction in a Rat Model Using Electrical Stimulation

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2025

This video demonstrates a procedure to induce tissue damage or infarction in the pons of an anesthetized rat using electrical stimulation.

Preparation and Culture of Chicken Auditory Brainstem Slices

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Cited by 17 •

2011

The chicken auditory brainstem is comprised of nuclei responsible for binaural sound processing. A single coronal slice preparation maintains the entire circuitry while the cultured approach provides a unique preparation to study the development of neuronal structure and auditory function at the molecular, cellular and network levels.

In Ovo Electroporation in the Chicken Auditory Brainstem

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Cited by 6 •

2017

Auditory brainstem neurons of avians and mammals are specialized for fast neural encoding, a fundamental process for normal hearing functions. These neurons arise from distinct precursors of embryonic hindbrain. We present techniques utilizing electroporation to express genes in the hindbrain of chicken embryos to study gene function during auditory development.

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