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Acute Myocardial Infarction in Rats
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Acute Myocardial Infarction in Rats

Acute Myocardial Infarction in Rats

DOI:
10.3791/2464-v

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07:45 min

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February 16, 2011

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, , , ,
1Department of Internal Medicine, Division of Cardiology,University of Texas Medical Branch, 2Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy,University of Houston (UH), Texas Medical Center

Chapters

  • 00:00Title
  • 01:49Preparing the Operating Area
  • 02:33Preparation and Intubation of Rats
  • 03:58Transient Left Anterior Descending (LAD) Artery Ligation
  • 06:02Histological Evaluation of the Ischemia Reperfusion
  • 07:14Conclusion

Summary

Automatic Translation

Automatic Translation

The rat model of acute myocardial infarction (AMI) is useful to study the consequence of a MI on cardiac pathophysiological and physiological function.

Tags

Acute Myocardial InfarctionHeart FailureBiomedical ResearchCardiovascular DiseasesAnimal ModelsMyocardial IschemiaIschemia-reperfusionPressure-overloadCardiac HypertrophyTransverse Aortic ConstrictionMyocardial InfarctionCardiovascular MorbidityMortalityArteriosclerosisSurgical InterventionMyocardiumVentricular RemodelingInfarcted Border ZoneRemote Non-infarcted MyocardiumMyocyte ApoptosisNecrosisHemodynamic LoadIntracellular SignalingLV DilatationHypertrophyVentricular Shape DistortionCollagen Scar FormationPathological RemodelingWall StressesProgressive DilatationScar FormationMyocardial Contractile Function

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