Friedlander Waveform

The Friedlander waveform is an idealized pressure-time profile used to represent the air-blast signature of an explosion, making transient blast exposure easier to describe and compare. It models a near-instantaneous rise to peak overpressure, followed by an approximately exponential decay during the positive-pressure phase and, in some formulations, a lower-amplitude negative phase. Key parameters include peak overpressure, positive-phase duration, and impulse, which together characterize the loading applied to a target. In neuroscience, Friedlander waveforms support controlled simulations and experiments on blast-induced traumatic brain injury by linking exposure conditions to pressure transmission, tissue deformation, and neurological outcomes.

Friedlander Waveform - Related Videos

Education

JoVE Core - Electrical Engineering

Effective Value of a Periodic Waveform

0 Views •

2024

The concept of effective value, the root mean square (RMS) value, is crucial in understanding electrical circuits and power delivery. This idea emerges from the necessity to measure the effectiveness of a voltage or current source in supplying power to a resistive load. The effective value of a periodic current represents the direct current (DC) that conveys the same average power to a resistor as the periodic current itself. This concept is crucial when assessing AC circuits. To determine the...

Research

JoVE Journal - Neuroscience
Free Sample

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

0 Views •

Cited by 1 •

2022

This article describes the semi-automated measurement of the amplitudes and latencies of the first five peaks and troughs in the auditory brainstem response waveform. An additional routine compiles and annotates the data into a spreadsheet for experimenter analysis. These free computer routines are executed using the open-source statistical package R.

High-precision Electromagnetic Flowmeter with Empty Pipe Detection via Complex Programmable Logic Device-based Waveform Recognition

0 Views •

2025

This study improves electromagnetic flowmeter accuracy by optimizing excitation waveforms, applying multi-stage filtering, and using Complex Programmable Logic Device (CPLD)-based rectification. A novel waveform-based empty pipe detection method enhances reliability. Experiments show 0.1% accuracy within 0.1-15 m/s, validating industrial applicability.

Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery

0 Views •

Cited by 15 •

2021

Here we present a step-by-step protocol to generate mature human retinal organoids and utilize them in a photoreceptor toxicity assay to identify pharmaceutical candidates for the age-related retinal degenerative disease macular telangiectasia type 2 (MacTel).

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens

0 Views •

2020

The opsono-adherence assay is an alternative method to the opsono-phagocytic killing assay to evaluate the opsonic functions of antibodies in vaccine development.

View All Results

FAQs

Related Topics