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Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
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Neuroscience
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JoVE Journal Neuroscience
Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R

DOI:
10.3791/64737-v

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06:01 min

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December 09, 2022

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,
1Department of Biomedical Genetics,University of Rochester Medical Center, 2Department of Neuroscience, Ernst J. Del Monte Institute for Neuroscience,University of Rochester Medical Center

Chapters

  • 00:04Introduction
  • 00:50Preparing the Auditory Brainstem Response (ABR) Data for Analysis
  • 01:39Installing the Required Packages and Loading the Data
  • 02:26Obtaining the Preliminary Analysis with FindPeaks.R
  • 02:58Verifying the Preliminary Analysis
  • 03:53Compiling and Visualizing the Dataset
  • 04:51Results: Analysis of Auditory Brainstem Response (ABR) Data by Manual and FindPeaks.R
  • 05:25Conclusion

Summary

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This article describes the semi-automated measurement of the amplitudes and latencies of the first five peaks and troughs in the auditory brainstem response waveform. An additional routine compiles and annotates the data into a spreadsheet for experimenter analysis. These free computer routines are executed using the open-source statistical package R.

Tags

Keywords: Auditory Brainstem ResponseABRWaveform AnalysisSemi-automated AnalysisR ScriptsPeak AmplitudeLatencyHearing ThresholdsBrainstem ActivityPre-cognitive Auditory ProcessingDiagnosisASCII FileIHSRStudioTidyverseShinyPlotlyZooFindpeaks.rSeetrace Click.rTime.csvBatch Processing

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