Nucleus Accumbens Caudate Putamen

The nucleus accumbens, caudate, and putamen are interconnected regions of the striatum, a major part of the basal ganglia that helps regulate motivation, learning, movement, and action selection. They integrate excitatory signals from the cerebral cortex with modulatory dopamine input from the midbrain, shaping activity through direct and indirect basal ganglia pathways. The nucleus accumbens is especially important for reward processing and reinforcement learning, whereas the caudate and putamen contribute strongly to goal-directed behavior, habit formation, and motor control. Studying these circuits helps explain addiction, Parkinson’s disease, Huntington’s disease, compulsive behaviors, and other neurological or psychiatric conditions.

Nucleus Accumbens Caudate Putamen - Related Videos

Research

JoVE EoE - Neuronal Culture Techniques

Co-culturing of Ventral Hippocampal and Nucleus Accumbens

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2025

This video demonstrates the process of preparing ventral hippocampal and nucleus accumbens tissues from mouse brains for co-culture. Neurons extend projections to form synaptic connections between the ventral hippocampal and nucleus accumbens tissues. This method allows studying neuronal interactions between these two brain regions, offering insights into cognition, behavior, and neurological disorders.

Identification of Dopamine D1-Alpha Receptor Within Rodent Nucleus Accumbens by an Innovative RNA In Situ Detection Technology

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Cited by 9 •

2018

Identification of dopamine D1-alpha receptor in the nucleus accumbens is critical for clarifying D1 receptor dysfunction during a central nervous system disease. We performed a novel RNA in situ hybridization assay to visualize single RNA molecules in a specific brain area.

Presynaptic Dopamine Dynamics in Striatal Brain Slices with Fast-scan Cyclic Voltammetry

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Cited by 18 •

2012

Using fast-scan cyclic voltammetry to measure electrically evoked presynaptic dopamine dynamics in striatal brain slices.

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

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2025

Intrahepatic cholangiocarcinoma of the caudate lobe is a challenge for many surgeons due to its unique location. Here, we present a protocol to show the step-by-step details of laparoscopic left hemihepatectomy combined with caudate lobe resection for cholangiocarcinoma.

Education

JoVE Core - Anatomy and Physiology

The Nucleus

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2023

The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles. Arrangement of DNA within Nucleus The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...

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