Rotor Rod Test

The Rotor Rod Test is a behavioral assay that measures motor coordination, balance, and endurance in laboratory animals, making it a useful tool in neuroscience research. During the test, an animal walks on a rotating rod that may maintain a constant speed or accelerate, and researchers record the latency to fall; improved performance can also reflect motor learning across repeated trials. The assay helps characterize motor impairments associated with neurological injury, disease, or experimental treatments and can evaluate the effects of drugs on movement. Results are commonly interpreted alongside other behavioral and physiological measures to distinguish coordination deficits from changes in motivation or strength.

Rotor Rod Test - Related Videos

Research

JoVE Journal - Bioengineering
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Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells

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Cited by 17 •

2012

Fluorescence Lifetime Imaging (FLIM) has emerged as a key technique to image the environment and interaction of specific proteins and dyes in living cells. FLIM of fluorescent molecular rotors allows mapping of viscosity in living cells.

Research

JoVE Journal - Engineering

How to Build a Vacuum Spring-transport Package for Spinning Rotor Gauges

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Cited by 1 •

2016

Here we describe how to build a robust spring-transport mechanism for a spinning rotor gauge. This device securely immobilizes the rotor and keeps it under vacuum during transportation. We also describe packaging that minimizes the risk of damage during transport. Tests show our design works for typical shocks during transport.

Education

JoVE Science Education - Basic Biology

Rodent Identification II

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2015

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN Animal records must be accurately maintained to ensure that data collection is correct. Records range from maintaining information on cage cards to having a detailed database with all of the relevant information on each animal. The primary component of recordkeeping is the individual identification of research animals. There are a variety of methods suitable for identifying mice and rats. This...

Considerations for Rodent Surgery

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2016

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning,...

Environmental Enrichment for Rodents

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2026

All animal procedures described here must be conducted in accordance with institutional animal ethics guidelines and approved by IACUC. All procedures must follow the principles of the 3Rs—Replacement, Reduction, and Refinement—and must be performed by trained personnel. Environmental enrichment involves objects and practices that encourage natural behaviors, improve psychological well-being, and promote better welfare in laboratory rodents. Environmental enrichment should be tailored to the...

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