Martin Seligman

Martin Seligman is an American psychologist best known for shaping positive psychology, the scientific study of strengths, well-being, and conditions that help people and communities thrive. His research on learned helplessness showed how repeated exposure to uncontrollable events can produce passive behavior and expectations of failure, while later work examined how optimism, meaning, engagement, relationships, and accomplishment support well-being. In psychology, these findings inform interventions that build resilience, reframe pessimistic interpretations, and strengthen adaptive behaviors. Seligman’s theories and measurement frameworks continue to influence clinical practice, education, organizational research, and studies of mental health and human flourishing.

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Research

JoVE Journal - Biochemistry
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Preparation of Sample Support Films in Transmission Electron Microscopy using a Support Floatation Block

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Cited by 10 •

2021

Sample preparation for cryo-electron microscopy (cryo-EM) is a significant bottleneck in the structure determination workflow of this method. Here, we provide detailed methods for using an easy-to-use, three-dimensionally printed block for the preparation of support films to stabilize samples for transmission EM studies.

Research

JoVE Journal - Biology

Virus-induced Gene Silencing (VIGS) in Nicotiana benthamiana and Tomato

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Cited by 159 •

2009

Description of a virus-induced gene silencing (VIGS) method for knock-down of gene expression in Nicotiana benthamiana and tomato.

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants

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Cited by 23 •

2009

A cell death-based assay for PTI in Nicotiana benthamiana plants is described.

3D Organotypic Co-culture Model Supporting Medullary Thymic Epithelial Cell Proliferation, Differentiation and Promiscuous Gene Expression

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Cited by 15 •

2015

Studying medullary thymic epithelial cells in vitro has been largely unsuccessful, as current 2D culture systems do not mimic the in vivo scenario. The 3D culture system described herein - a modified skin organotypic culture model - has proven superior in recapitulating mTEC proliferation, differentiation and maintenance of promiscuous gene expression.

Synthesis of Ligand-free CdS Nanoparticles within a Sulfur Copolymer Matrix

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2016

Herein we present a method to synthesize ligand-free cadmium sulfide (CdS) nanoparticles based on a unique sulfur copolymer. The sulfur copolymer operates as a high temperature solvent and a sulfur source during the nanoparticle synthesis and stabilizes the nanoparticles after the reaction.

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