Qing Li

Qing Li

Mechanical Engineering and Materials Science, Duke University

Affiliated withDuke UniversitySun Yat-sen UniversityUniversity of Michigan, Ann Arbor

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Research Area

Biography

Dr. Li is an Associate Professor in the Division of Gastroenetrology, Department of Internal Medicine, the University of Texas Medical Branch at Galveston. He received

his Master’s Degree in Organic Chemistry from Guangxi Normal University, and a PhD in Biochemistry and Molecular Biology from Central South University, China.

He received his postdoctoral training in Dr. Roderick Dashwood's laboratory at the Linus Pauling Institute, Oregon State University, where he worked on molecular mechanisms and chemoprevention of colorectal cancer. He joined UTMB as a faculty member in 2006.

Dr. Li’s research interests lie in inflammatory bowel disease (IBD), a complex GI disease associated with lifelong medical attention, poor quality of life and huge economic burden, as well as in IBD-associated disorders, including colitis-associated cancer and IBD-induced cardiovascular diseases. Decades of research suggests that the pathogenesis of IBD, including Crohn’s disease and ulcerative colitis, involves abnormal gut microbiota, immune response dysregulation, environmental factors and genetic susceptibility. Specifically, Dr. Li’s research interests include:

• Epigenetic and bacterial contributions to the development of IBD and colitis-associated cancer (CAC);

• Molecular mechanisms underlying IBD-associated cardiovascular disorders;

• Identification of biomarkers and therapeutic targets in IBD and CAC;

• Development of small molecule drugs targeting TRAF6 and MMP7 in inflammatory diseases;

• Phytochemicals as chemopreventive agents against IBD and extraintestinal manifestations of IBD.

JoVE Journal Publications

ArticleTotal : 4
Year
Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope
Publication title

Cited by 4

2019
2018
2021
2025

Other Publications

Article
Year
The influence of central corneal thickness and corneal curvature and axial length on the measurement of intraocular pressure.

Yan ke xue bao = Eye science| PubMed ID: 15510750

2002
2007
2007
[E1A gene transfection of human undifferentiated thyroid cancer cell line HTC/3 by nanoparticles].

Zhonghua zhong liu za zhi [Chinese journal of oncology]| PubMed ID: 18478924

2007
[Cytotoxicity of the secondary metabolites of Marine Mangrove Fungus Paecilomyces sp. tree 1-7 on human hepatoma cell line HepG2].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials| PubMed ID: 18998570

2008
[Exploration of lymphangiogenesis in alkali burned human cornea].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology| PubMed ID: 19573329

2009
[A comparison of three methods in establishing transplanted model of VX2 tongue carcinoma in rabbits].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology| PubMed ID: 19637489

2009
Serum uric acid levels and neuromyelitis optica.

Journal of neurology| PubMed ID: 20094725

2010
2010
2012
2013
2013
2013
2013
2014
Single molecule mechanical manipulation for studying biological properties of proteins, DNA, and sugars.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology| PubMed ID: 24347439

2014
2014
2015
2014
Divalent metal ion-based catalytic mechanism of the Nudix hydrolase Orf153 (YmfB) from Escherichia coli.

Acta crystallographica. Section D, Biological crystallography| PubMed ID: 24816099

2014
Structure of human endonuclease V as an inosine-specific ribonuclease.

Acta crystallographica. Section D, Biological crystallography| PubMed ID: 25195743

2014
2014
2014
Capturing the mechanical unfolding pathway of a large protein with coiled-coil probes.

Angewandte Chemie (International ed. in English)| PubMed ID: 25339429

2014
2015
2015
2015
2015
2016
A targeted IL-15 fusion protein with potent anti-tumor activity.

Cancer biology & therapy| PubMed ID: 26176990

2015
2016
2015
In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis.

Chemico-biological interactions| PubMed ID: 26362498

2015
2015
2015
A novel bispecific antibody, S-Fab, induces potent cancer cell killing.

Journal of immunotherapy (Hagerstown, Md. : 1997)| PubMed ID: 26448579

2015
2015
2015
2016
2016
2016
2016
Research on supporting mounts of spheres in measurement of gravitational constant G.

The Review of scientific instruments| PubMed ID: 27036796

2016
2016
2016
2016
2016
Bispecific antibodies in cancer immunotherapy.

Human vaccines & immunotherapeutics| PubMed ID: 27249163

2016
2016
2016
2016
2016
2016
2016
2016
2016
2016
2017
2017
2017
2017
2017
2017
2018
2017
2017
2017
2017
2017
2017
2017
2017
2017
A Bispecific Antibody Based on Pertuzumab Fab Has Potent Antitumor Activity.

Journal of immunotherapy (Hagerstown, Md. : 1997)| PubMed ID: 29232309

2018
2018
2018
2018
2018
Surface-Assisted Alkane Polymerization: Investigation on Structure-Reactivity Relationship.

Journal of the American Chemical Society| PubMed ID: 29432011

2018
2018
2018
2018
2018
2018
2018
2018
Prevalence and risk factors for fatigue among breast cancer survivors on aromatase inhibitors.

European journal of cancer (Oxford, England : 1990)| PubMed ID: 30014974

2018
2018
2018
2020
2021
2016
2017
2019
2019
2020
2021
2021
2021
2022
2023
2023
2024
2024
Association of aerobic and muscle-strengthening activity with chronic low back pain: population-based study.

The spine journal : official journal of the North American Spine Society| PubMed ID: 39343241

2024
2024
2024
Inebilizumab for Treatment of IgG4-Related Disease.

The New England journal of medicine| PubMed ID: 39541094

2025
2025
2025
2025
2025
2025