Stephen H. Tsang

Harkness Eye Institute, Columbia University College of Physicians and Surgeons

Affiliated withColumbia University College of Physicians and Surgeons University of Iowa Columbia University

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 39	2011
Publication title Cited by 19	2011
Publication title Cited by 35	2012
Publication title Cited by 7	2017

Other Publications

Article	Year
The positive role of the carboxyl terminus of the gamma subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo. Vision research\| PubMed ID: 11853759	2002
Retinal degeneration and RPE transplantation in Rpe65(-/-) mice. Investigative ophthalmology & visual science\| PubMed ID: 12356839	2002
Stationary night blindness or progressive retinal degeneration in mice carrying different alleles of PDE gamma. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 12700134	2003
Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness. Human mutation\| PubMed ID: 17044014	2007
Transducin translocation in rods is triggered by saturation of the GTPase-activating complex. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17267570	2007
Novel phenotypic and genotypic findings in X-linked retinoschisis. Archives of ophthalmology\| PubMed ID: 17296904	2007
Autofluorescence imaging in a case of benign familial fleck retina. Archives of ophthalmology\| PubMed ID: 17502520	2007
Electronegative electroretinogram associated with topiramate toxicity and vitelliform maculopathy. Documenta ophthalmologica. Advances in ophthalmology\| PubMed ID: 17912565	2008
Non-vascular vision loss in pseudoxanthoma elasticum. Documenta ophthalmologica. Advances in ophthalmology\| PubMed ID: 18034271	2008
Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18305241	2008
Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors. Experimental eye research\| PubMed ID: 18472095	2008
Preferred retinal locus in macular disease: characteristics and clinical implications. Retina (Philadelphia, Pa.)\| PubMed ID: 18628727	2008
Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q). Investigative ophthalmology & visual science\| PubMed ID: 18658088	2008
A novel mutation and phenotypes in phosphodiesterase 6 deficiency. American journal of ophthalmology\| PubMed ID: 18723146	2008
Phenotype-genotype correlations in autosomal dominant retinitis pigmentosa caused by RHO, D190N. Current eye research\| PubMed ID: 19085385	2008
G1961E mutant allele in the Stargardt disease gene ABCA4 causes bull's eye maculopathy. Experimental eye research\| PubMed ID: 19217903	2009
Benign panretinal uniform radial linear-shaped flecks. Clinical & experimental ophthalmology\| PubMed ID: 19278486	2008
A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease. Investigative ophthalmology & visual science\| PubMed ID: 19324865	2009
Fundus autofluorescence in cone dystrophy. Documenta ophthalmologica. Advances in ophthalmology\| PubMed ID: 19340470	2009
Case report: autofluorescence imaging and phenotypic variance in a sibling pair with early-onset retinal dystrophy due to defective CRB1 function. Current eye research\| PubMed ID: 19401883	2009
Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium. Ophthalmology\| PubMed ID: 19410955	2009
Structural assessment of hyperautofluorescent ring in patients with retinitis pigmentosa. Retina (Philadelphia, Pa.)\| PubMed ID: 19584660	2009
Light-dependent phosphorylation of the gamma subunit of cGMP-phophodiesterase (PDE6gamma) at residue threonine 22 in intact photoreceptor neurons. Biochemical and biophysical research communications\| PubMed ID: 19878658	2009
Erythropoetin receptor expression in the human diabetic retina. BMC research notes\| PubMed ID: 19930719	2009
Rapid and noninvasive imaging of retinal ganglion cells in live mouse models of glaucoma. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 19937134	2010
Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa. Transplantation\| PubMed ID: 20164818	2010
Fundus autofluorescence, optical coherence tomography, and electroretinogram findings in choroidal sclerosis. Retina (Philadelphia, Pa.)\| PubMed ID: 20224472	2010
Autofluorescence and High-Resolution OCT Findings Revealed Ciliopathy in Senior-Loken Syndrome. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye\| PubMed ID: 20337316	2010
Fundus autofluorescence and optical coherence tomography of congenital grouped albinotic spots. Retina (Philadelphia, Pa.)\| PubMed ID: 20539258	2010
Vitamin A deficiency in New York City. Lancet\| PubMed ID: 20663549	2010
Loss of peripapillary sparing in non-group I Stargardt disease. Experimental eye research\| PubMed ID: 20696155	2010
shRNA knockdown of guanylate cyclase 2e or cyclic nucleotide gated channel alpha 1 increases photoreceptor survival in a cGMP phosphodiesterase mouse model of retinitis pigmentosa. Journal of cellular and molecular medicine\| PubMed ID: 20950332	2011
Unilateral electronegative ERG in a presumed central retinal artery occlusion. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 21139671	2010
Macular dystrophy in Heimler syndrome. Ophthalmic genetics\| PubMed ID: 21366429	2011
Allelic and phenotypic heterogeneity in ABCA4 mutations. Ophthalmic genetics\| PubMed ID: 21510770	2011
Function of the asparagine 74 residue of the inhibitory Î³-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo. Cellular signalling\| PubMed ID: 21616145	2011
Quantification of peripapillary sparing and macular involvement in Stargardt disease (STGD1). Investigative ophthalmology & visual science\| PubMed ID: 21873672	2011
Lentivirus-mediated expression of cDNA and shRNA slows degeneration in retinitis pigmentosa. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 21885480	2011
Structural and functional changes associated with normal and abnormal fundus autofluorescence in patients with retinitis pigmentosa. Retina (Philadelphia, Pa.)\| PubMed ID: 21909055	2012
Analysis of the ABCA4 gene by next-generation sequencing. Investigative ophthalmology & visual science\| PubMed ID: 21911583	2011
Effect of the ILE86TER mutation in the Î³ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling. Cellular signalling\| PubMed ID: 21920434	2012
Autofluorescence imaging and spectral-domain optical coherence tomography in incomplete congenital stationary night blindness and comparison with retinitis pigmentosa. American journal of ophthalmology\| PubMed ID: 21920492	2012
Disruption in Bruch membrane in patients with Stargardt disease. Ophthalmic genetics\| PubMed ID: 22060670	2012
The inner segment/outer segment border seen on optical coherence tomography is less intense in patients with diminished cone function. Investigative ophthalmology & visual science\| PubMed ID: 22110066	2011
Progressive Constriction of the Hyperautofluorescent Ring in Retinitis Pigmentosa. American journal of ophthalmology\| PubMed ID: 22137208	2011
Unilateral retinitis pigmentosa: a proposal of genetic pathogenic mechanisms. European journal of ophthalmology\| PubMed ID: 22139616	2011
HYPERAUTOFLUORESCENT RING IN AUTOIMMUNE RETINOPATHY. Retina (Philadelphia, Pa.)\| PubMed ID: 22218149	2012
Mice with a D190N mutation in the gene encoding rhodopsin: a model for human autosomal dominant Retinitis Pigmentosa. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 22252712	2012
Infrared Imaging and Optical Coherence Tomography Reveal Early-Stage Astrocytic Hamartomas Not Detectable by Fundoscopy. American journal of ophthalmology\| PubMed ID: 22310082	2012
Familial discordance in Stargardt disease. Molecular vision\| PubMed ID: 22312191	2012