Cam Patterson

McAllister Heart Institute, University of North Carolina at Chapel Hill

Affiliated withUniversity of North Carolina at Chapel Hill New York-Presbyterian Hospital/Weill-Cornell Medical Center

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 12	2013
Publication title Cited by 4	2013
Publication title Cited by 2	2014

Other Publications

Article	Year
A new gun in town: the U box is a ubiquitin ligase domain. Science's STKE : signal transduction knowledge environment\| PubMed ID: 11805346	2002
Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts. Circulation\| PubMed ID: 11864929	2002
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. The EMBO journal\| PubMed ID: 12006493	2002
Things have changed: cell cycle dysregulation and smooth muscle cell dysfunction in atherogenesis. Ageing research reviews\| PubMed ID: 12039437	2002
A noncoding RNA regulates human protease-activated receptor-1 gene during embryogenesis. Biochimica et biophysica acta\| PubMed ID: 12084570	2002
Tiny dancers: the integrin-growth factor nexus in angiogenic signaling. The Journal of cell biology\| PubMed ID: 12105178	2002
Protein quality control: U-box-containing E3 ubiquitin ligases join the fold. Trends in biochemical sciences\| PubMed ID: 12114026	2002
Mitochondrial integrity and function in atherogenesis. Circulation\| PubMed ID: 12147534	2002
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12239347	2002
HIV therapies and atherosclerosis: answers or questions? Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12426201	2002
Welcome to the machine: a cardiologist's introduction to protein folding and degradation. Circulation\| PubMed ID: 12438302	2002
Evidence for association of coronary sinus levels of hepatocyte growth factor and collateralization in human coronary disease. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 12521946	2003
Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol. Molecular biology of the cell\| PubMed ID: 12529448	2003
C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation. Archives of biochemistry and biophysics\| PubMed ID: 12559985	2003
Break the cycle: the role of cell-cycle modulation in the prevention of vasculoproliferative diseases. Cell cycle (Georgetown, Tex.)\| PubMed ID: 12734427	2003
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. The EMBO journal\| PubMed ID: 12773386	2003
AtCHIP, a U-box-containing E3 ubiquitin ligase, plays a critical role in temperature stress tolerance in Arabidopsis. Plant physiology\| PubMed ID: 12805616	2003
Thrombin and vascular development: a sticky subject. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12807713	2003
The Ponzo effect: endothelial progenitor cells appear on the horizon. Circulation\| PubMed ID: 12821584	2003
Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells. Molecular and cellular biology\| PubMed ID: 12832480	2003
BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Molecular and cellular biology\| PubMed ID: 12897139	2003
HoxB5 is an upstream transcriptional switch for differentiation of the vascular endothelium from precursor cells. Molecular and cellular biology\| PubMed ID: 12897140	2003
Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP. The Journal of biological chemistry\| PubMed ID: 14507928	2003
CHIP activates HSF1 and confers protection against apoptosis and cellular stress. The EMBO journal\| PubMed ID: 14532117	2003
PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase. Journal of cellular physiology\| PubMed ID: 14603533	2004
Catecholamine-induced vascular wall growth is dependent on generation of reactive oxygen species. Circulation research\| PubMed ID: 14656924	2004
Age-related changes in matrix metalloproteinase-9 regulation in cultured mouse aortic smooth muscle cells. Experimental gerontology\| PubMed ID: 14724072	2004
p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. The Journal of biological chemistry\| PubMed ID: 14966113	2004
Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein. Journal of molecular biology\| PubMed ID: 15001357	2004
Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery f... Brain research. Molecular brain research\| PubMed ID: 15046863	2004
Younger than yesterday: is vascular senescence a two-way street? Circulation research\| PubMed ID: 15059938	2004
An androgen receptor NH2-terminal conserved motif interacts with the COOH terminus of the Hsp70-interacting protein (CHIP). The Journal of biological chemistry\| PubMed ID: 15107424	2004
CHIP: a link between the chaperone and proteasome systems. Cell stress & chaperones\| PubMed ID: 15115282	2003
LE-PAS, a novel Arnt-dependent HLH-PAS protein, is expressed in limbic tissues and transactivates the CNS midline enhancer element. Brain research. Molecular brain research\| PubMed ID: 15363889	2004
Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase. The Journal of biological chemistry\| PubMed ID: 15466472	2004
Universal mouse reference RNA derived from neonatal mice. BioTechniques\| PubMed ID: 15470901	2004
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. The Journal of clinical investigation\| PubMed ID: 15489953	2004
Blood pressure control goes nuclear. Circulation research\| PubMed ID: 15514165	2004
A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters. Molecular and cellular biology\| PubMed ID: 15572660	2004
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophy. The Journal of cell biology\| PubMed ID: 15596539	2004
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15601779	2004
A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase. The Journal of cell biology\| PubMed ID: 15611333	2004
CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 15665051	2005
Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes. Cardiovascular research\| PubMed ID: 15721860	2005
Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 15746439	2005
The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways. The Journal of biological chemistry\| PubMed ID: 15845543	2005
Cystic fibrosis transmembrane conductance regulator as a model substrate to study endoplasmic reticulum protein quality control in mammalian cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15917641	2005
C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis. Cell stress & chaperones\| PubMed ID: 16038411	2005
Mechanisms of endothelial differentiation in embryonic vasculogenesis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16123328	2005
Even flow: shear cues vascular development. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16127024	2005
Regulation of the cytoplasmic quality control protein degradation pathway by BAG2. The Journal of biological chemistry\| PubMed ID: 16169850	2005
Direct identification of ubiquitination sites on ubiquitin-conjugated CHIP using MALDI mass spectrometry. Journal of proteome research\| PubMed ID: 16212406	2005
Bone morphogenetic proteins and vascular differentiation: BMPing up vasculogenesis. Thrombosis and haemostasis\| PubMed ID: 16270622	2005
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP. The Journal of cell biology\| PubMed ID: 16344307	2005
ATP stimulates MMP-2 release from human aortic smooth muscle cells via JNK signaling pathway. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 16361361	2006
A combined strategy to reduce restenosis for vascular tissue engineering applications. Biotechnology progress\| PubMed ID: 16454490	2006
The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16469848	2006
Abciximab-associated thrombocytopenia after previous tirofiban-related thrombocytopenia. Pharmacotherapy\| PubMed ID: 16503724	2006
A salty salute: progenitor cell therapies and no-option heart disease. American heart journal\| PubMed ID: 16504614	2006
Search and destroy: the role of protein quality control in maintaining cardiac function. Journal of molecular and cellular cardiology\| PubMed ID: 16516914	2006
CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70. Nature\| PubMed ID: 16554822	2006
Gene expression profile signatures indicate a role for Wnt signaling in endothelial commitment from embryonic stem cells. Circulation research\| PubMed ID: 16601226	2006
Comparative effects of paclitaxel and rapamycin on smooth muscle migration and survival: role of AKT-dependent signaling. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16645158	2006
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16807328	2006
CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation. The Journal of biological chemistry\| PubMed ID: 16831871	2006
Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP. The Biochemical journal\| PubMed ID: 16895519	2006
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator. Cell\| PubMed ID: 16901789	2006
Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP. The Journal of biological chemistry\| PubMed ID: 16931512	2006
Into the heart: the emerging role of the ubiquitin-proteasome system. Journal of molecular and cellular cardiology\| PubMed ID: 16949602	2006
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies. The Journal of biological chemistry\| PubMed ID: 17098737	2007
Gene expression profiles identify a role for cyclooxygenase 2-dependent prostanoid generation in BMP6-induced angiogenic responses. Blood\| PubMed ID: 17119124	2007
Brain CHIP: removing the culprits in neurodegenerative disease. Trends in molecular medicine\| PubMed ID: 17127096	2007
2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells. Cancer research\| PubMed ID: 17234781	2007
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circulation research\| PubMed ID: 17272810	2007
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. The Journal of clinical investigation\| PubMed ID: 17304350	2007
CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism. Human molecular genetics\| PubMed ID: 17317785	2007
The bitter end: the ubiquitin-proteasome system and cardiac dysfunction. Circulation\| PubMed ID: 17372187	2007
Diminished GATA4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury. The Journal of biological chemistry\| PubMed ID: 17525155	2007
Chaperone functions of the E3 ubiquitin ligase CHIP. The Journal of biological chemistry\| PubMed ID: 17545168	2007
Characterization of a model to independently study regression of ventricular hypertrophy. The Journal of surgical research\| PubMed ID: 17574596	2007
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. Journal of molecular and cellular cardiology\| PubMed ID: 17618647	2007
ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism. Molecular and cellular biology\| PubMed ID: 17636018	2007
Selection and initial characterization of novel peptide ligands that bind specifically to human blood outgrowth endothelial cells. Biotechnology and bioengineering\| PubMed ID: 17657770	2007
PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. Journal of molecular and cellular cardiology\| PubMed ID: 17662997	2008
ERK signaling is a central regulator for BMP-4 dependent capillary sprouting. Cardiovascular research\| PubMed ID: 17850776	2007
Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 17873020	2007
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins. The Journal of clinical investigation\| PubMed ID: 17965779	2007
Twin layers of lightning: a new role for the chaperone Hsp90 in angiogenesis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 17975116	2008
The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle. Cell metabolism\| PubMed ID: 17983583	2007
CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 18079406	2008
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors. The Journal of cell biology\| PubMed ID: 18158328	2007
Partners in crime: how two Sox proteins cooperate to specify arterial fate. Circulation research\| PubMed ID: 18174468	2008
You spin me round: MaFBx/Atrogin-1 feeds forward on FOXO transcription factors (like a record). Cell cycle (Georgetown, Tex.)\| PubMed ID: 18235241	2008
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18256189	2008
Akt and CHIP coregulate tau degradation through coordinated interactions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18292230	2008
Molecular characterization of human breast tumor vascular cells. The American journal of pathology\| PubMed ID: 18403594	2008
CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control. Molecular and cellular biology\| PubMed ID: 18411298	2008
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. The Journal of cell biology\| PubMed ID: 18504303	2008
Selective endothelial cell attachment to peptide-modified terpolymers. Biomaterials\| PubMed ID: 18556061	2008
Therapeutic options for premature coronary artery disease. Current treatment options in cardiovascular medicine\| PubMed ID: 18647585	2008
Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males. BMC medical genomics\| PubMed ID: 18710571	2008
BMPER is an endothelial cell regulator and controls bone morphogenetic protein-4-dependent angiogenesis. Circulation research\| PubMed ID: 18787191	2008
Zinc fingers in the pizza pie aorta. Circulation research\| PubMed ID: 18818412	2008
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Molecular cell\| PubMed ID: 18922468	2008
Brothers and sisters: molecular insights into arterial-venous heterogeneity. Circulation research\| PubMed ID: 18948631	2008
Build it up-Tear it down: protein quality control in the cardiac sarcomere. Cardiovascular research\| PubMed ID: 18974044	2009
The opening act: vasculogenesis and the origins of circulation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19008532	2009
Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2. Nature structural & molecular biology\| PubMed ID: 19029896	2008
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases. Archives of biochemistry and biophysics\| PubMed ID: 19103148	2009
Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile. The Journal of thoracic and cardiovascular surgery\| PubMed ID: 19154930	2009
Muscle ring finger 1 mediates cardiac atrophy in vivo. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19168726	2009
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19196961	2009
Torturing a blood vessel. Nature medicine\| PubMed ID: 19197284	2009
A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling. The Journal of cell biology\| PubMed ID: 19221194	2009
CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation. Molecular and cellular biology\| PubMed ID: 19237536	2009
Breast cancer quality control. Nature cell biology\| PubMed ID: 19255569	2009
SDF-1alpha stimulates JNK3 activity via eNOS-dependent nitrosylation of MKP7 to enhance endothelial migration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19307591	2009
New insights into bone morphogenetic protein signaling: focus on angiogenesis. Current opinion in hematology\| PubMed ID: 19346940	2009
HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving angiopoietin-2. Cardiovascular research\| PubMed ID: 19403561	2009
Black and white: rapamycin as a regulator of cardiac mTOR signaling. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19454842	2009
Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway. Cancer research\| PubMed ID: 19458075	2009
Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program. The Journal of biological chemistry\| PubMed ID: 19465479	2009
C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1. The Journal of biological chemistry\| PubMed ID: 19483080	2009
Cardiac muscle ring finger-1 increases susceptibility to heart failure in vivo. Circulation research\| PubMed ID: 19498199	2009
Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease. Future cardiology\| PubMed ID: 19543439	2008
Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer. The Journal of biological chemistry\| PubMed ID: 19648119	2009
KrÃ¼ppel-like factor 15 regulates BMPER in endothelial cells. Cardiovascular research\| PubMed ID: 19767294	2010
Seek and destroy: the ubiquitin----proteasome system in cardiac disease. Current hypertension reports\| PubMed ID: 19895750	2009
Minireview: Won't get fooled again: the nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 20016041	2010
Stable patterns of gene expression regulating carbohydrate metabolism determined by geographic ancestry. PloS one\| PubMed ID: 20016837	2009
BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20042706	2010
Hard luck stories: the reality of endothelial progenitor cells continues to fall short of the promise. Circulation\| PubMed ID: 20142453	2010
The FoxO family in cardiac function and dysfunction. Annual review of physiology\| PubMed ID: 20148668	2010
Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease. Circulation research\| PubMed ID: 20167943	2010
Gyrate: CCM3 dances with a different angiogenic partner. Science signaling\| PubMed ID: 20484115	2010
Development of the endothelium: an emphasis on heterogeneity. Seminars in thrombosis and hemostasis\| PubMed ID: 20490975	2010
A good idea: a physician's perspective on genetic counseling for hypertrophic cardiomyopathy. Journal of cardiovascular translational research\| PubMed ID: 20560009	2009
mTORC1 links protein quality and quantity control by sensing chaperone availability. The Journal of biological chemistry\| PubMed ID: 20605781	2010
Cardiac muscle ring finger-1--friend or foe? Trends in cardiovascular medicine\| PubMed ID: 20685572	2010
Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 20724525	2010
Closer to fine: fewer steps to endothelial stemness. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20844268	2010
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow. American journal of respiratory cell and molecular biology\| PubMed ID: 20870896	2011
CHIP-dependent p53 regulation occurs specifically during cellular senescence. Free radical biology & medicine\| PubMed ID: 20974249	2011
Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease. Circulation\| PubMed ID: 20975010	2010
Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21071685	2011
Evaluating age-associated phenotypes in a mouse model of protein dyshomeostasis. Methods (San Diego, Calif.)\| PubMed ID: 21167942	2011
Regulation of AMPK by the ubiquitin proteasome system. The American journal of pathology\| PubMed ID: 21224036	2011
Tearin' up my heart: proteolysis in the cardiac sarcomere. The Journal of biological chemistry\| PubMed ID: 21257759	2011
Efficient in vivo selection of a novel tumor-associated peptide from a phage display library. Molecules (Basel, Switzerland)\| PubMed ID: 21258297	2011
The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun. The American journal of pathology\| PubMed ID: 21356357	2011
NF-ÎºB inhibition protects against tumor-induced cardiac atrophy in vivo. The American journal of pathology\| PubMed ID: 21356358	2011
Regulation of ankyrin repeat and suppressor of cytokine signalling box protein 4 expression in the immortalized murine endothelial cell lines MS1 and SVR: a role for tumour necrosis factor a... Cell biochemistry and function\| PubMed ID: 21506136	2011
The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus. PloS one\| PubMed ID: 21673995	2011
Rise above: muscle ring-finger-1 (MURF1) regulation of cardiomyocyte size and energy metabolism. Transactions of the American Clinical and Climatological Association\| PubMed ID: 21686210	2011
Bone morphogenetic protein endothelial cell precursor-derived regulator regulates retinal angiogenesis in vivo in a mouse model of oxygen-induced retinopathy. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21737784	2011
Tear me down: role of calpain in the development of cardiac ventricular hypertrophy. Circulation research\| PubMed ID: 21817165	2011
Regulation of the calpain and ubiquitin-proteasome systems in a canine model of muscular dystrophy. Muscle & nerve\| PubMed ID: 21826685	2011
Reconstitution of CHIP E3 ubiquitin ligase activity. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21898230	2011
BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium. Blood\| PubMed ID: 21900199	2011
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) colocalizes with insulin receptor substrate 4 (IRS4) in the hypothalamic neurons and mediates IRS4 degradation. BMC neuroscience\| PubMed ID: 21955513	2011
Back to your heart: ubiquitin proteasome system-regulated signal transduction. Journal of molecular and cellular cardiology\| PubMed ID: 22085703	2012
BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice. The Journal of biological chemistry\| PubMed ID: 22144676	2012
Life is a pattern: vascular assembly within the embryo. Frontiers in bioscience (Elite edition)\| PubMed ID: 22202036	2012
The expanding world of post-translational modifications. Journal of molecular and cellular cardiology\| PubMed ID: 22265974	2012
p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction. Circulation research\| PubMed ID: 22267842	2012
A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. American journal of respiratory and critical care medicine\| PubMed ID: 22312013	2012
Recovery from decompensated heart failure is associated with a distinct, phase-dependent gene expression profile. The Journal of surgical research\| PubMed ID: 22480839	2012
The ubiquitin-proteasome system and cardiovascular disease. Progress in molecular biology and translational science\| PubMed ID: 22727426	2012
Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22772758	2012
LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis. Circulation research\| PubMed ID: 22777006	2012
PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response. The Journal of clinical investigation\| PubMed ID: 22797300	2012
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy\| PubMed ID: 22966490	2012
Lysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis. Molecular pharmacology\| PubMed ID: 23087261	2013
ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF. Molecular and cellular biology\| PubMed ID: 23129809	2013
BMPER regulates cardiomyocyte size and vessel density in vivo. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 23200275	2013
Proteotoxicity and cardiac dysfunction--Alzheimer's disease of the heart? The New England journal of medicine\| PubMed ID: 23363499	2013
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo. Cell biochemistry and function\| PubMed ID: 23512667	2013
Carboxyl terminus of Hsp70-interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise. Cell biochemistry and function\| PubMed ID: 23553918	2013
A novel monoclonal antibody to secreted frizzled-related protein 2 inhibits tumor growth. Molecular cancer therapeutics\| PubMed ID: 23604067	2013
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response. The EMBO journal\| PubMed ID: 23612611	2013
Proteotoxicity and cardiac dysfunction. The New England journal of medicine\| PubMed ID: 23635068	2013
Antagonism and synergy between extracellular BMP modulators Tsg and BMPER to balance blood vessel formation. Journal of cell science\| PubMed ID: 23641068	2013
Development of a new positron emission tomography tracer for targeting tumor angiogenesis: synthesis, small animal imaging, and radiation dosimetry. Molecules (Basel, Switzerland)\| PubMed ID: 23676470	2013
Diggin' on U(biquitin): A Novel Method for the Identification of Physiological E3 Ubiquitin Ligase Substrates. Cell biochemistry and biophysics\| PubMed ID: 23695782	2013
Inhibition of BMP activity protects epithelial barrier function in lung injury. The Journal of pathology\| PubMed ID: 23716395	2013