Dynamic Compliance Analysis

Dynamic compliance analysis is a method for quantifying how a material, tissue, or biological system deforms in response to forces that change over time. It typically applies controlled, time-dependent stress or pressure and measures the resulting strain or volume change, revealing compliance, viscoelastic behavior, and the phase relationship between applied force and deformation. In bioengineering, these measurements help characterize soft biomaterials, engineered tissues, and biological structures under conditions that better reflect physiological loading than static tests. The resulting mechanical profiles support material selection, device design, tissue modeling, and evaluation of how engineered systems may perform during repeated or dynamic use.

Dynamic Compliance Analysis - Related Videos

Research

JoVE Journal - Bioengineering

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions

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Cited by 15 •

2013

We describe a correlative microscopy method that combines high-speed 3D live-cell fluorescent light microscopy and high-resolution cryo-electron tomography. We demonstrate the capability of the correlative method by imaging dynamic, small HIV-1 particles interacting with host HeLa cells.

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience

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Cited by 6 •

2014

This manuscript describes a protocol that applies comprehensive profiling for analysis of transcriptional programs induced in specific brain nuclei of rodents following behavioral paradigms. Herein, this approach is illustrated in the context of profiling genes induced in the nucleus accumbens (NAc) of mice following acute cocaine exposure, utilizing microfluidic qPCR arrays.

High-resolution Imaging and Analysis of Individual Astral Microtubule Dynamics in Budding Yeast

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Cited by 33 •

2017

Budding yeast is an advantageous model for studying microtubule dynamics in vivo due to its powerful genetics and the simplicity of its microtubule cytoskeleton. The following protocol describes how to transform and culture yeast cells, acquire confocal microscopy images, and quantitatively analyze microtubule dynamics in living yeast cells.

Education

JoVE Science Education - Engineering

Dynamics of Structures

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA It is rare nowadays that a whole year goes by without a major earthquake event wreaking havoc somewhere around the world. In some cases, like the 2005 Banda Ache earthquake in Indonesia, the damage involved large geographic areas and casualties in the six figures. In general, the number and intensity of earthquakes is not increasing, however, the vulnerability of the built environment is...

Automated Analysis of Dynamic Ca2+ Signals in Image Sequences

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Cited by 28 •

2014

Here a novel region of interest analysis protocol based on sorting best-fit ellipses assigned to regions of positive signal within two-dimensional time lapse image sequences is demonstrated. This algorithm may enable investigators to comprehensively analyze physiological Ca2+ signals with minimal user input and bias.

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